Self-Expanding Prostheses for Transcatheter Aortic Valve Replacement

Robert Kumar, Azeem Latib, Antonio Colombo, Carlos E. Ruiz

Research output: Contribution to journalArticlepeer-review


Transcatheter aortic valve replacement (TAVR) has emerged as an alternative to surgical aortic valve replacement in patients who are considered high surgical risk or inoperable due to advanced age and comorbidities. Randomized trial and registry data have demonstrated the safety and efficacy of TAVR in such patients. Currently available transcatheter heart valves (THVs) employ either balloon-expandable or self-expanding designs, and several new designs have shown promising early results. Differences in valve design may offer specific advantages for accurate deployment and minimizing complications. This article reviews several designs of self-expanding THVs that are currently available or have undergone successful implantation in humans. Additional studies are required to compare the relative performance of these devices.

Original languageEnglish
Pages (from-to)596-609
Number of pages14
JournalProgress in Cardiovascular Diseases
Issue number6
Publication statusPublished - 2014


  • Aortic stenosis
  • Aortic valve
  • Percutaneous
  • Self-expanding
  • Transcatheter

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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