TY - JOUR
T1 - Self-disorders and clinical high risk for psychosis
T2 - An empirical study in help-seeking youth attending community mental health facilities
AU - Raballo, Andrea
AU - Pappagallo, Elena
AU - Dell Erba, Alice
AU - Lo Cascio, Nella
AU - Patane, Martina
AU - Gebhardt, Eva
AU - Boldrini, Tommaso
AU - Terzariol, Laura
AU - Angelone, Massimiliano
AU - Trisolini, Alberto
AU - Girardi, Paolo
AU - Nastro, Paolo Fiori
PY - 2016
Y1 - 2016
N2 - Anomalous subjective experiences involving an alteration of the basic sense of self (ie, Self-disorder [SD]) are emerging as a core marker of schizophrenia spectrum disorders with potential impact on current early detection strategies as well. In this study, we wished to field-test the prevalence of SD in a clinical sample of adolescent/young adult help-seekers at putative risk for psychosis attending standard community mental health facilities in Italy. Participants (n = 47), aged between 14 and 25, underwent extensive psychopathological evaluations with current semi-structured tools to assess Clinical High Risk (CHR) state (ie, Structured Interview for Prodromal Syndromes/Scale of Prodromal Symptoms [SIPS/SOPS], Schizophrenia Proneness Instrument-Adult/Child and Youth [SPI-A/CY]). SD aggregated in CHR subjects as compared to the non-CHR and revealed substantial association with sub-psychotic symptoms (SIPS), subjective experience of cognitive and cognitive-perceptual vulnerability (basic symptoms) and functional level (Global Assessment of functioning). Moreover, a combination of the 2 approaches (ie, CHR plus SD) enabled further closing-in on a subgroup of CHR with lower global functioning. The results confirm SD's relevance for the early profiling of youths at potential high risk for psychosis.
AB - Anomalous subjective experiences involving an alteration of the basic sense of self (ie, Self-disorder [SD]) are emerging as a core marker of schizophrenia spectrum disorders with potential impact on current early detection strategies as well. In this study, we wished to field-test the prevalence of SD in a clinical sample of adolescent/young adult help-seekers at putative risk for psychosis attending standard community mental health facilities in Italy. Participants (n = 47), aged between 14 and 25, underwent extensive psychopathological evaluations with current semi-structured tools to assess Clinical High Risk (CHR) state (ie, Structured Interview for Prodromal Syndromes/Scale of Prodromal Symptoms [SIPS/SOPS], Schizophrenia Proneness Instrument-Adult/Child and Youth [SPI-A/CY]). SD aggregated in CHR subjects as compared to the non-CHR and revealed substantial association with sub-psychotic symptoms (SIPS), subjective experience of cognitive and cognitive-perceptual vulnerability (basic symptoms) and functional level (Global Assessment of functioning). Moreover, a combination of the 2 approaches (ie, CHR plus SD) enabled further closing-in on a subgroup of CHR with lower global functioning. The results confirm SD's relevance for the early profiling of youths at potential high risk for psychosis.
KW - Basic symptoms
KW - Clinical high risk
KW - Positive symptoms
KW - Prodrome
KW - Psychosis
KW - Self
KW - Subjective experience
UR - http://www.scopus.com/inward/record.url?scp=84979243226&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84979243226&partnerID=8YFLogxK
U2 - 10.1093/schbul/sbv223
DO - 10.1093/schbul/sbv223
M3 - Article
AN - SCOPUS:84979243226
SN - 0586-7614
VL - 42
SP - 926
EP - 932
JO - Schizophrenia Bulletin
JF - Schizophrenia Bulletin
IS - 4
ER -