TY - JOUR
T1 - Role of radiotherapy in the treatment of epidemic Kaposi's sarcoma
T2 - Experience with sixty-five cases
AU - Piccinno, Roberta
AU - Caccialanza, Massimo
AU - Cusini, Marco
PY - 1995
Y1 - 1995
N2 - Background: Treatment of Kaposi's sarcoma (KS) associated with HIV infection should improve often disfiguring lesions, with an acceptable cosmetic outcome; relieve associated signs and symptoms (pain and edema); and have no adverse effects on the patient's already impaired immune status. Objective: Our purpose was to determine the role of x-ray therapy in the treatment of KS. Methods: Contact x-ray therapy and half-deep x-ray therapy were used to treat 594 lesions in 65 patients with KS, who were observed for 1 to 43 months (mean, 9 months). Results: Complete remission was achieved with pigmentation in 405 lesions (68.3%), with good cosmetic results in 105 (17.7%), and with hypopigmentation in three (0.5%). In 80 lesions (13.5%) only size reduction or pain palliation were achieved. Fourteen lesions (2.4%) relapsed 2 to 9 months after treatment. Conclusion: X-ray therapy is well tolerated and meets the specified requirements for the treatment of KS.
AB - Background: Treatment of Kaposi's sarcoma (KS) associated with HIV infection should improve often disfiguring lesions, with an acceptable cosmetic outcome; relieve associated signs and symptoms (pain and edema); and have no adverse effects on the patient's already impaired immune status. Objective: Our purpose was to determine the role of x-ray therapy in the treatment of KS. Methods: Contact x-ray therapy and half-deep x-ray therapy were used to treat 594 lesions in 65 patients with KS, who were observed for 1 to 43 months (mean, 9 months). Results: Complete remission was achieved with pigmentation in 405 lesions (68.3%), with good cosmetic results in 105 (17.7%), and with hypopigmentation in three (0.5%). In 80 lesions (13.5%) only size reduction or pain palliation were achieved. Fourteen lesions (2.4%) relapsed 2 to 9 months after treatment. Conclusion: X-ray therapy is well tolerated and meets the specified requirements for the treatment of KS.
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U2 - 10.1016/0190-9622(95)91339-4
DO - 10.1016/0190-9622(95)91339-4
M3 - Article
C2 - 7538517
AN - SCOPUS:0029042693
SN - 0190-9622
VL - 32
SP - 1000
EP - 1003
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 6
ER -