Robotic Splenectomy for Isolated Splenic Recurrence of Endometrial Adenocarcinoma

Valerio Gallotta, Marco D'Indinosante, Camilla Nero, Maria Teresa Giudice, Carmine Conte, Claudio Lodoli, Gian Franco Zannoni, Anna Fagotti, Giovanni Scambia

Research output: Contribution to journalArticlepeer-review


Study Objective: To demonstrate management of a rare case of an isolated intraparenchymal splenic metastasis of endometrial cancer with robotic-assisted surgery. Design: Case report (Canadian Task Force Classification III). Setting: A 55-year-old patient with a history of endometrial cancer was found to have a splenic lesion on a follow-up examination. She underwent surgical staging, involving total hysterectomy, bilateral salpingo-oopherectomy, pelvic lymphadenectomy, and peritoneal washing, in 2014, and the final pathological findings showed an endometrioid endometrial adenocarcinoma, International Federation of Gynecology and Obstetrics stage IB G2. Multidisciplinary counseling was provided, and the patient opted for strict medical surveillance. At 20 months after the primary treatment, the patient experienced a vaginal cuff recurrence and refused radiation therapy. She instead underwent robotic surgery, followed by 6 cycles of carboplatin 6 AUC and paclitaxel 175 mg/m2. Seventeen months later, a positron emission tomography/computed tomography scan revealed a 3-cm intraparenchymal lesion of the spleen, and robotic splenectomy was scheduled. The Institutional Review Board approved this study. Intervention: The operative time was 90 minutes, and blood loss was <50 mL. The operation was performed successfully, with no intraoperative and postoperative complications. Histopathological analysis showed a 3-cm intraparenchymal splenic lesion. The patient was discharged on day +2, and 46 days later started adjuvant chemotherapy based on carboplatin 6 AUC and doxorubicin (Caelyx) 30 mg/m2. At a 2-month follow-up, the patient was disease-free and in good general condition. Conclusion: This case demonstrates the successful robotic management of recurrent endometrial cancer.

Original languageEnglish
Pages (from-to)774-775
Number of pages2
JournalJournal of Minimally Invasive Gynecology
Issue number5
Publication statusPublished - Jul 1 2018


  • Endometrial cancer
  • Endometrial recurrence
  • Robotic surgery
  • Splenectomy

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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