TY - JOUR
T1 - Robot-Assisted, Laparoscopic, and Open Radical Cystectomy
T2 - Pre-Operative Data of 1400 Patients From The Italian Radical Cystectomy Registry
AU - Busetto, Gian Maria
AU - D’Agostino, Daniele
AU - Colicchia, Michele
AU - Palmer, Katie
AU - Artibani, Walter
AU - Antonelli, Alessandro
AU - Bianchi, Lorenzo
AU - Bocciardi, Aldo
AU - Brunocilla, Eugenio
AU - Carini, Marco
AU - Carrieri, Giuseppe
AU - Cormio, Luigi
AU - Falagario, Ugo Giovanni
AU - De Berardinis, Ettore
AU - Sciarra, Alessandro
AU - Leonardo, Costantino
AU - Del Giudice, Francesco
AU - Maggi, Martina
AU - de Cobelli, Ottavio
AU - Ferro, Matteo
AU - Musi, Gennaro
AU - Ercolino, Amelio
AU - Di Maida, Fabrizio
AU - Gallina, Andrea
AU - Introini, Carlo
AU - Mearini, Ettore
AU - Cochetti, Giovanni
AU - Minervini, Andrea
AU - Montorsi, Francesco
AU - Schiavina, Riccardo
AU - Serni, Sergio
AU - Simeone, Claudio
AU - Parma, Paolo
AU - Serao, Armando
AU - Mangano, Mario Salvatore
AU - Pomara, Giorgio
AU - Ditonno, Pasquale
AU - Simonato, Alchiede
AU - Romagnoli, Daniele
AU - Crestani, Alessandro
AU - Porreca, Angelo
N1 - Funding Information:
Appreciation for contribution and data collection is expressed to Gianluca D’Elia (Roma), Stefano Zaramella (Biella), Salvatore Bartolotta (Catania), Mario Falsaperla (Catania), Antonio Cisternino (San Giovanni Rotondo), Tommaso Cai (Trento), Pietro Cozzupuoli (Reggio Calabria), Luca Cindolo (Roma), Francesco Beniamin (Treviso), Carlo Alberto Sepich (Versilia), Vincenzo De Marco (Verona), Alessandro Mastrorosa (Bari), Giancarlo Peracchia (Modena), Vito Mancini (Foggia), Alberto Abrate (Palermo), Silvia Secco (Milano), Massimiliano Chessa (Nuoro), Mauro Gacci (Firenze), Grazino Vignoli (Firenze), Riccardo Campi (Firenze), Sandro Benvenuti (Aosta), Alessandro Terrin (Chioggia), Bernardi Diego (Cuneo), Filippo Annino (San Donato di Arezzo), Michele Amenta (Portogruaro).
Publisher Copyright:
Copyright © 2022 Busetto, D’Agostino, Colicchia, Palmer, Artibani, Antonelli, Bianchi, Bocciardi, Brunocilla, Carini, Carrieri, Cormio, Falagario, De Berardinis, Sciarra, Leonardo, Del Giudice, Maggi, de Cobelli, Ferro, Musi, Ercolino, Di Maida, Gallina, Introini, Mearini, Cochetti, Minervini, Montorsi, Schiavina, Serni, Simeone, Parma, Serao, Mangano, Pomara, Ditonno, Simonato, Romagnoli, Crestani and Porreca.
PY - 2022/5/5
Y1 - 2022/5/5
N2 - Introduction: The Italian Radical Cystectomy Registry (RIC) is an observational prospective study aiming to understand clinical variables and patient characteristics associated with short- and long-term outcomes among bladder cancer (BC) patients undergoing radical cystectomy (RC). Moreover, it compares the effectiveness of three RC techniques - open, robotic, and laparoscopic. Methods: From 2017 to 2020, 1400 patients were enrolled at one of the 28 centers across Italy. Patient characteristics, as well as preoperative, postoperative, and follow-up (3, 6, 12, and 24 months) clinical variables and outcomes were collected. Results: Preoperatively, it was found that patients undergoing robotic procedures were younger (p<.001) and more likely to have undergone preoperative neoadjuvant chemotherapy (p<.001) and BCG instillation (p<.001). Hypertension was the most common comorbidity among all patients (55%), and overall, patients undergoing open and laparoscopic RC had a higher Charlson Comorbidities Index (CCI) compared to robotic RC (p<.001). Finally, laparoscopic patients had a lower G-stage classification (p=.003) and open patients had a higher ASA score (p<.001). Conclusion: The present study summarizes the characteristic of patients included in the RIC. Future results will provide invaluable information about outcomes among BC patients undergoing RC. This will inform physicians about the best techniques and course of care based on patient clinical factors and characteristics.
AB - Introduction: The Italian Radical Cystectomy Registry (RIC) is an observational prospective study aiming to understand clinical variables and patient characteristics associated with short- and long-term outcomes among bladder cancer (BC) patients undergoing radical cystectomy (RC). Moreover, it compares the effectiveness of three RC techniques - open, robotic, and laparoscopic. Methods: From 2017 to 2020, 1400 patients were enrolled at one of the 28 centers across Italy. Patient characteristics, as well as preoperative, postoperative, and follow-up (3, 6, 12, and 24 months) clinical variables and outcomes were collected. Results: Preoperatively, it was found that patients undergoing robotic procedures were younger (p<.001) and more likely to have undergone preoperative neoadjuvant chemotherapy (p<.001) and BCG instillation (p<.001). Hypertension was the most common comorbidity among all patients (55%), and overall, patients undergoing open and laparoscopic RC had a higher Charlson Comorbidities Index (CCI) compared to robotic RC (p<.001). Finally, laparoscopic patients had a lower G-stage classification (p=.003) and open patients had a higher ASA score (p<.001). Conclusion: The present study summarizes the characteristic of patients included in the RIC. Future results will provide invaluable information about outcomes among BC patients undergoing RC. This will inform physicians about the best techniques and course of care based on patient clinical factors and characteristics.
KW - Italy
KW - multicenter
KW - radical cystectomy
KW - RIC
KW - urinary bladder neoplasms
UR - http://www.scopus.com/inward/record.url?scp=85130623905&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85130623905&partnerID=8YFLogxK
U2 - 10.3389/fonc.2022.895460
DO - 10.3389/fonc.2022.895460
M3 - Article
AN - SCOPUS:85130623905
SN - 2234-943X
VL - 12
JO - Frontiers in Oncology
JF - Frontiers in Oncology
M1 - 895460
ER -