Risk of postoperative recurrence and postoperative management of Crohn's disease

Research output: Contribution to journalArticlepeer-review


Crohn's disease (CD) is a chronic inflammatory disease of the digestive tract with systemic manifestations. Etiology is unknown, even if immunological, genetic and environmental factors are involved. The majority of CD patients require surgery during their lifetime due to progressive bowel damage, but, even when all macroscopic lesions have been removed by surgery, the disease recurs in most cases. Postoperative management represents therefore a crucial mean for preventing recurrence. Several drugs and approaches have been proposed to achieve this aim. Endoscopic inspection of the ileocolic anastomosis within 1 year from surgery is widely encouraged, given that endoscopic recurrence is one of the greatest predictors for clinical recurrence. A strategy should be planned only after stratifying patients according to their individual risk of recurrence, avoiding unnecessary therapies when possible benefits are reduced, and selecting high-risk patients for more aggressive intervention.

Original languageEnglish
Pages (from-to)3213-3219
Number of pages7
JournalWorld Journal of Gastroenterology
Issue number27
Publication statusPublished - Jul 21 2011


  • Crohn's disease
  • Postoperative treatment
  • Recurrence
  • Surgery
  • Surveillance

ASJC Scopus subject areas

  • Gastroenterology


Dive into the research topics of 'Risk of postoperative recurrence and postoperative management of Crohn's disease'. Together they form a unique fingerprint.

Cite this