Right hemispheric dysfunction in a case of pure progressive aphemia: Fusion of multimodal neuroimaging

Paolo Vitali, Flavio Nobili, Umberto Raiteri, Michela Canfora, Marco Rosa, Piero Calvini, Nicola Girtler, Giovanni Regesta, Guido Rodriguez

Research output: Contribution to journalArticlepeer-review

Abstract

This article describes the unusual case of a 60-year-old woman suffering from pure progressive aphemia. The fusion of multimodal neuroimaging (MRI, perfusion SPECT) implicated the right frontal lobe, especially the inferior frontal gyrus. This area also showed the greatest functional MRI activation during the performance of a covert phonemic fluency task. Results are discussed in terms of bihemispheric language representation. The fusion of three sets of neuroimages has aided in the interpretation of the patient's cognitive brain dysfunction.

Original languageEnglish
Pages (from-to)97-107
Number of pages11
JournalPsychiatry Research - Neuroimaging
Volume130
Issue number1
DOIs
Publication statusPublished - Jan 15 2004

Keywords

  • Conjugate gradients
  • Focal atrophy
  • Functional magnetic resonance imaging
  • Single photon emission computed tomography

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Radiology Nuclear Medicine and imaging
  • Biological Psychiatry
  • Psychology(all)

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