Abstract
This article describes the unusual case of a 60-year-old woman suffering from pure progressive aphemia. The fusion of multimodal neuroimaging (MRI, perfusion SPECT) implicated the right frontal lobe, especially the inferior frontal gyrus. This area also showed the greatest functional MRI activation during the performance of a covert phonemic fluency task. Results are discussed in terms of bihemispheric language representation. The fusion of three sets of neuroimages has aided in the interpretation of the patient's cognitive brain dysfunction.
Original language | English |
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Pages (from-to) | 97-107 |
Number of pages | 11 |
Journal | Psychiatry Research - Neuroimaging |
Volume | 130 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 15 2004 |
Keywords
- Conjugate gradients
- Focal atrophy
- Functional magnetic resonance imaging
- Single photon emission computed tomography
ASJC Scopus subject areas
- Psychiatry and Mental health
- Radiology Nuclear Medicine and imaging
- Biological Psychiatry
- Psychology(all)