INFEZIONE DA RHODOCOCCUS EQUI IN PAZIENTI HIV POSITIVI. CONSIDERAZIONI SU DI UNA CASISTICA PERSONALE

Translated title of the contribution: Rhodococcus equi infection in HIV infected patients. Comments on personal case-file

R. Maserati, R. Giacchino, P. Vitulo, C. Nascimbene, U. Pandolfi, M. Benedetti, G. Chichino

Research output: Contribution to journalArticlepeer-review

Abstract

Infection by Rhodococcus equi represents a rare but already documented event in HIV-infected individuals, leading to the development of chronic granulomatous lesions in lungs and in other organs as well; these lesions respond only partially to antimicrobials. We recently diagnosed (through specimens obtained with BAL and/or transbronchial biopsy in all cases and through blood cultures in 2 pts.) 4 cases of pulmonary rhodococcosis in 4 males with a mean age of 29.7 yrs. (26 to 34) and a mean CD4+ lymphocyte count of 53/mcL (19 to 106). Lung involvement was localized at lower right lobe and middle right lobe in 1 case each, while the 2 remaining pts. showed a lesion at the upper right lobe. Combinations of 2 or more antibiotics were administered in all cases and in 2 pts. a surgical intervention was performed, without any major post-surgical complications. Our experience seems to point out that the surgical ablation of chronic inflammatory lesions caused by R. equi in lungs should be evaluated even in AIDS pts.

Translated title of the contributionRhodococcus equi infection in HIV infected patients. Comments on personal case-file
Original languageItalian
Pages (from-to)1072-1078
Number of pages7
JournalGiornale di Malattie Infettive e Parassitarie
Volume46
Issue number12
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Parasitology

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