Revaccination against hepatitis B virus of non-responding and low-responding infants immunised at birth. A parallel evaluation of rubella and tetanus vaccine

C. Belloni; C. Tinelli; P. Orsolini; A. Pistorio; A. Avanzini; A. Moretta; R. Gulminetti; O. Bogliolo; G. Chirico; G. Rondini

doi:10.1016/S0264-410X(97)80917-6

Revaccination against hepatitis B virus of non-responding and low-responding infants immunised at birth. A parallel evaluation of rubella and tetanus vaccine

C. Belloni, C. Tinelli, P. Orsolini, A. Pistorio, A. Avanzini, A. Moretta, R. Gulminetti, O. Bogliolo, G. Chirico, G. Rondini

Research output: Contribution to journal › Article › peer-review

Abstract

The aim of the present study was to identify the true extent of the non-responsiveness in infants born from HBsAg-negative mothers, vaccinated against Hepatitis B Virus (HBV) at birth. Sixty-four non- and low-responding infants, selected from an initial cohort of 2009, were given two additional doses of recombinant HBV vaccine between the tenth and the twelfth months of age. A parallel evaluation was conducted on the response to anti-rubella and anti-tetanus vaccine. Only two infants remained non-responders, whereas 68% of the non-responders and 94% of the low responders after the primary vaccination scheduled developed antibody titres over 100 mIU ml^-1. No significant relationship between the specific antibody level against HBV and against rubella or tetanus 1 month after vaccination was observed.

Original language	English
Pages (from-to)	399-402
Number of pages	4
Journal	Vaccine
Volume	16
Issue number	4
DOIs	https://doi.org/10.1016/S0264-410X(97)80917-6
Publication status	Published - Feb 1998

Keywords

HBV
Immunisation
New-born
Non-responsiveness
Rubella
Tetanus

ASJC Scopus subject areas

Immunology
Microbiology
Virology
Infectious Diseases
Public Health, Environmental and Occupational Health
veterinary(all)

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10.1016/S0264-410X(97)80917-6

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Belloni, C., Tinelli, C., Orsolini, P., Pistorio, A., Avanzini, A., Moretta, A., Gulminetti, R., Bogliolo, O., Chirico, G., & Rondini, G. (1998). Revaccination against hepatitis B virus of non-responding and low-responding infants immunised at birth. A parallel evaluation of rubella and tetanus vaccine. Vaccine, 16(4), 399-402. https://doi.org/10.1016/S0264-410X(97)80917-6

Belloni, C, Tinelli, C , Orsolini, P , Pistorio, A , Avanzini, A , Moretta, A , Gulminetti, R, Bogliolo, O, Chirico, G & Rondini, G 1998, 'Revaccination against hepatitis B virus of non-responding and low-responding infants immunised at birth. A parallel evaluation of rubella and tetanus vaccine', Vaccine, vol. 16, no. 4, pp. 399-402. https://doi.org/10.1016/S0264-410X(97)80917-6

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abstract = "The aim of the present study was to identify the true extent of the non-responsiveness in infants born from HBsAg-negative mothers, vaccinated against Hepatitis B Virus (HBV) at birth. Sixty-four non- and low-responding infants, selected from an initial cohort of 2009, were given two additional doses of recombinant HBV vaccine between the tenth and the twelfth months of age. A parallel evaluation was conducted on the response to anti-rubella and anti-tetanus vaccine. Only two infants remained non-responders, whereas 68% of the non-responders and 94% of the low responders after the primary vaccination scheduled developed antibody titres over 100 mIU ml-1. No significant relationship between the specific antibody level against HBV and against rubella or tetanus 1 month after vaccination was observed.",

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author = "C. Belloni and C. Tinelli and P. Orsolini and A. Pistorio and A. Avanzini and A. Moretta and R. Gulminetti and O. Bogliolo and G. Chirico and G. Rondini",

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AU - Tinelli, C.

AU - Orsolini, P.

AU - Pistorio, A.

AU - Avanzini, A.

AU - Moretta, A.

AU - Gulminetti, R.

AU - Bogliolo, O.

AU - Chirico, G.

AU - Rondini, G.

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AB - The aim of the present study was to identify the true extent of the non-responsiveness in infants born from HBsAg-negative mothers, vaccinated against Hepatitis B Virus (HBV) at birth. Sixty-four non- and low-responding infants, selected from an initial cohort of 2009, were given two additional doses of recombinant HBV vaccine between the tenth and the twelfth months of age. A parallel evaluation was conducted on the response to anti-rubella and anti-tetanus vaccine. Only two infants remained non-responders, whereas 68% of the non-responders and 94% of the low responders after the primary vaccination scheduled developed antibody titres over 100 mIU ml-1. No significant relationship between the specific antibody level against HBV and against rubella or tetanus 1 month after vaccination was observed.

KW - HBV

KW - Immunisation

KW - New-born

KW - Non-responsiveness

KW - Rubella

KW - Tetanus

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Revaccination against hepatitis B virus of non-responding and low-responding infants immunised at birth. A parallel evaluation of rubella and tetanus vaccine

Abstract

Keywords

ASJC Scopus subject areas

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