Restless Legs Syndrome in Children and Adolescents

Lourdes M DelRosso, Maria Paola Mogavero, Argelinda Baroni, Oliviero Bruni, Raffaele Ferri

Research output: Contribution to journalReview articlepeer-review


Children with psychiatric comorbidities frequently are referred for evaluation of sleep complaints. Common sleep symptoms can include difficulty falling asleep, frequent nocturnal awakening, restless sleep, and symptoms of restless legs syndrome (RLS). The understanding of the sleep condition in relation to the psychiatric comorbidity often is a challenge to the physician and often sleep disorders remain undiagnosed, untreated, or undertreated. Restless legs syndrome has been associated with psychiatric comorbidities and with certain medications, such as antidepressants, antihistamines, and antipsychotics. This article reviews the presentation of RLS and restless sleep, the association with psychiatric comorbidities, and treatment options.

Original languageEnglish
Pages (from-to)143-157
Number of pages15
JournalChild and Adolescent Psychiatric Clinics of North America
Issue number1
Publication statusPublished - Jan 2021


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