Restless legs syndrome was the first isolated clinical manifestation in four siblings of a family with familial amyloid polyneuropathy. Clinical and electrophysiological evidence of peripheral neuropathy appeared after a variable time interval. Polysomnography showed abnormal sleep patterns and nocturnal myoclonus in all patients. The restless legs syndrome responded favourably to clonazepam.
|Number of pages||4|
|Journal||Journal of Neurology, Neurosurgery and Psychiatry|
|Publication status||Published - 1990|
ASJC Scopus subject areas
- Psychiatry and Mental health
- Neuropsychology and Physiological Psychology