Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation

Bruno Alfano, Mario Quarantelli, Arturo Brunetti, Michele Larobina, Eugenio M. Covelli, Enrico Tedeschi, Marco Salvatore

Research output: Contribution to journalArticlepeer-review


To assess the inter-study variability of a recently published unsupervised segmentation method (Magn. Reson. Med. 1997;37:84-93), 14 brain MR studies were performed in five normal subjects. Standard deviations for absolute and fractional volumes of intracranial compartments, which reflect the experimental variability, were smaller than 16.5 ml and 1.1%, respectively. By comparing the experimental component of the variability with the variability observed in our reference database, an estimate of the biological variability of the intracranial fractional volumes in the database population was obtained.

Original languageEnglish
Pages (from-to)497-499
Number of pages3
JournalMagnetic Resonance in Medicine
Issue number3
Publication statusPublished - Mar 1998


  • Brain
  • Magnetic resonance imaging
  • Segmentation
  • Volume measurement

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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