Repeated vaccinations do not improve specific immune defenses against Hepatitis B in non-responder health care workers

Salvatore Zaffina; Valentina Marcellini; Anna Paola Santoro; Marco Scarsella; Vincenzo Camisa; Maria Rosaria Vinci; Anna Maria Musolino; Luciana Nicolosi; M. Manuela Rosado; Rita Carsetti

doi:10.1016/j.vaccine.2014.10.066

Repeated vaccinations do not improve specific immune defenses against Hepatitis B in non-responder health care workers

Salvatore Zaffina, Valentina Marcellini, Anna Paola Santoro, Marco Scarsella, Vincenzo Camisa, Maria Rosaria Vinci, Anna Maria Musolino, Luciana Nicolosi, M. Manuela Rosado, Rita Carsetti

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

Hepatitis B is a major infectious occupational hazard for health care workers and can be prevented with a safe and effective vaccine. The serum titer of anti-HBsAg antibodies is the most commonly used correlate of protection and post-vaccination anti-HBsAg concentrations of ≥10. mIU/ml are considered protective. Subjects with post-vaccination anti-HBsAg titers of

Original language	English
Pages (from-to)	6902-6910
Number of pages	9
Journal	Vaccine
Volume	32
Issue number	51
DOIs	https://doi.org/10.1016/j.vaccine.2014.10.066
Publication status	Published - 2014

Keywords

Anti-HBsAg specific antibodies
Hepatitis B vaccine
Memory B cells
Non-responders

ASJC Scopus subject areas

Immunology and Microbiology(all)
Infectious Diseases
Public Health, Environmental and Occupational Health
veterinary(all)
Molecular Medicine
Medicine(all)

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10.1016/j.vaccine.2014.10.066

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abstract = "Hepatitis B is a major infectious occupational hazard for health care workers and can be prevented with a safe and effective vaccine. The serum titer of anti-HBsAg antibodies is the most commonly used correlate of protection and post-vaccination anti-HBsAg concentrations of ≥10. mIU/ml are considered protective. Subjects with post-vaccination anti-HBsAg titers of ",

keywords = "Anti-HBsAg specific antibodies, Hepatitis B vaccine, Memory B cells, Non-responders",

author = "Salvatore Zaffina and Valentina Marcellini and Santoro, {Anna Paola} and Marco Scarsella and Vincenzo Camisa and Vinci, {Maria Rosaria} and Musolino, {Anna Maria} and Luciana Nicolosi and Rosado, {M. Manuela} and Rita Carsetti",

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AU - Zaffina, Salvatore

AU - Marcellini, Valentina

AU - Santoro, Anna Paola

AU - Scarsella, Marco

AU - Camisa, Vincenzo

AU - Vinci, Maria Rosaria

AU - Musolino, Anna Maria

AU - Nicolosi, Luciana

AU - Rosado, M. Manuela

AU - Carsetti, Rita

PY - 2014

Y1 - 2014

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KW - Anti-HBsAg specific antibodies

KW - Hepatitis B vaccine

KW - Memory B cells

KW - Non-responders

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Repeated vaccinations do not improve specific immune defenses against Hepatitis B in non-responder health care workers

Abstract

Keywords

ASJC Scopus subject areas

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