Reliability of the six-minute walk test in individuals with stroke: systematic review and meta-analysis

Alice Macchiavelli, Antonella Giffone, Francesco Ferrarello, Matteo Paci

Research output: Contribution to journalReview articlepeer-review


Purpose: The six-minute walking test (6MWT) is a simple and widely used measure of functional capacity. The aim of this systematic review is to summarize findings on reliability of 6MWT in subjects who have had a stroke. Methods: Two independent investigators conducted an extensive search in multidisciplinary electronic databases from inception to August 2019, and selected complete original studies on the reliability of the 6MWT used to assess individuals with stroke. Two reviewers independently extracted data and evaluated methodological quality. Outcome for meta-analysis was reliability, measured by intraclass correlation coefficient (ICC). In addition, standard error of measurement (SEM) and minimal detectable change (MDC) were recorded. Results: Of the 241 potentially relevant articles screened, 6 met inclusion criteria and 5 of them were included in meta-analysis. Combined correlation coefficient of.98 (confidence interval.98–.99) was found for test-retest reliability. Only one study investigated inter-rater and intra-rater reliability. SEM and MDC values were rarely reported. Conclusions: The 6MWT has high test-retest reliability, when used to assess individuals with stroke. Other types of reliability and SEM and MDC need further investigations in populations with a stroke.

Original languageEnglish
JournalNeurological Sciences
Publication statusE-pub ahead of print - Oct 2020


  • Outcome assessment
  • Outcomes
  • Reliability
  • Stroke
  • Walk test

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health


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