Relationship of flow rate with symptoms, quality of life and other clinical parameters in patients with LUTS suggestive of BPH

Aim: The uroflowmetry data of a selected number of patients who took part to the QUIBUS study (366 traces selected after quality control by a central panel of reviewer) were evaluated for their relationships with age, prostate volume, and IPSS and ICS-BPH scores. Waiting time, flow time, voided volume, maximum flow rate (Q _max) and average flow rate (Q _ave) were the flow variables considered for analysis. Only measurements with total voided volume exceeding 100 ml were included. Results: An increasing percentage of subjects with voided volume ave nor Q _max(p = n.s. at correlation analysis). In particular, Q _max was max and Q _ave, showing a worsening of urinary function for increasing values of prostate volume Q _max was negatively correlated with IPSS total score and with most single items with the exception of two storage symptoms such as repeated urination and nocturia). Accordingly, Q _max was inversely associated with the total score ICS-BPH for voiding symptoms to a higher extent (r = -0.31, p