Relationship between a wide range of alcohol consumptions, components of the insulin-like growth factor system and adiponectin

L. Dal Maso, C. La Vecchia, L. S A Augustin, C. S. Mantzoros, C. W C Kendall, S. Franceschi

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To explore the relation between a wide range of alcohol consumptions and levels of the components of insulin-like growth factor system (IGFs) and adiponectin in humans. Design: A cross-sectional study using controls from a case-control study on ovarian and endometrial cancer. Settings: The study included women hospitalized between 1999 and 2002 in Pordenone, Italy. Subjects: One hundred and eight cancer-free (controls) with a median age of 61 years (range 29-79 years), admitted for acute conditions unrelated to gynecologic, hormonal or metabolic disorders or diseases leading to dietary modifications. Interventions: Levels of IGF-I (total and free),total IGF-II, IGF-binding protein 1 (IGFBP-1), IGFBP-3 and adiponectin were individually measured, and their distributions across strata of alcohol consumption were tested by the Kruskal-Wallis statistic. Results: Median concentrations of total IGF-I were higher (P

Original languageEnglish
Pages (from-to)221-225
Number of pages5
JournalEuropean Journal of Clinical Nutrition
Volume61
Issue number2
DOIs
Publication statusPublished - Feb 2007

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

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