TY - JOUR
T1 - Regulation of ferritin synthesis in malignant and non-malignant lymphoid cells
AU - Cairo, Gaetano
AU - Vezzoni, Paolo
AU - Bardella, Lidia
AU - Schiaffonati, Luisa
AU - Rappocciolo, Emilia
AU - Levi, Sonia
AU - Arosio, Paolo
AU - Bernelli-Zazzera, Aldo
PY - 1986/9/16
Y1 - 1986/9/16
N2 - The different amounts of H-rich and L-rich isoferritins found in malignant and non malignant lymphoid cells are accompanied by proportional variations in the relative quantity of messenger RNAs for the H and L subunits of ferritin. The correlation between levels of messenger RNAs and proteins suggests that the amount of messenger RNA plays an important role in ferritin biosynthesis in these cells. The enhanced expression of ferritin messenger RNAs in some neoplastic cells is not caused by gross alterations in the structure of ferritin genes.
AB - The different amounts of H-rich and L-rich isoferritins found in malignant and non malignant lymphoid cells are accompanied by proportional variations in the relative quantity of messenger RNAs for the H and L subunits of ferritin. The correlation between levels of messenger RNAs and proteins suggests that the amount of messenger RNA plays an important role in ferritin biosynthesis in these cells. The enhanced expression of ferritin messenger RNAs in some neoplastic cells is not caused by gross alterations in the structure of ferritin genes.
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U2 - 10.1016/S0006-291X(86)80040-7
DO - 10.1016/S0006-291X(86)80040-7
M3 - Article
C2 - 3021135
AN - SCOPUS:0022543673
SN - 0006-291X
VL - 139
SP - 652
EP - 657
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -