TY - JOUR
T1 - Regional diastolic function by tissue Doppler echocardiography in systemic sclerosis
T2 - Correlation with clinical variables
AU - Rosato, Edoardo
AU - Maione, Stefania
AU - Vitarelli, Antonio
AU - Giunta, Anna
AU - Fontanella, Luca
AU - De Horatio, Laura Tanturri
AU - Cacciatore, Francesco
AU - Proietti, Michele
AU - Pisarri, Simonetta
AU - Salsano, Felice
PY - 2009/6
Y1 - 2009/6
N2 - The incidence of left ventricular (LV) diastolic dysfunction is increased in systemic sclerosis (SSc), while systolic dysfunction is present in a small percentage of patients. The aim of this study was to asses the LV "regional" diastolic abnormalities in SSc patients by the mean of Doppler tissue imaging (DTI). Echocardiographic echo-Doppler (DE) and DTI parameters were analyzed for 67 SSc patients: abnormal E/A ratio at DE was detected in 24, while abnormal e/a at DTI was observed in 41. A significant prevalence of DTI diastolic abnormalities in the segments reflecting longitudinal versus those reflecting radial LV motion was found. The segments of the basal regions of LV myocardium were significantly more involved than those of the middle portion. Linear correlation was observed between the extent of the diastolic abnormalities and the duration of disease. Longitudinal myocardial systolic velocities were significantly reduced in patients with abnormal e/a DTI.
AB - The incidence of left ventricular (LV) diastolic dysfunction is increased in systemic sclerosis (SSc), while systolic dysfunction is present in a small percentage of patients. The aim of this study was to asses the LV "regional" diastolic abnormalities in SSc patients by the mean of Doppler tissue imaging (DTI). Echocardiographic echo-Doppler (DE) and DTI parameters were analyzed for 67 SSc patients: abnormal E/A ratio at DE was detected in 24, while abnormal e/a at DTI was observed in 41. A significant prevalence of DTI diastolic abnormalities in the segments reflecting longitudinal versus those reflecting radial LV motion was found. The segments of the basal regions of LV myocardium were significantly more involved than those of the middle portion. Linear correlation was observed between the extent of the diastolic abnormalities and the duration of disease. Longitudinal myocardial systolic velocities were significantly reduced in patients with abnormal e/a DTI.
KW - Doppler tissue imaging
KW - Regional left ventricular systolic and diastolic function
KW - Systemic sclerosis
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U2 - 10.1007/s00296-008-0827-x
DO - 10.1007/s00296-008-0827-x
M3 - Article
C2 - 19112565
AN - SCOPUS:67349188868
SN - 0172-8172
VL - 29
SP - 913
EP - 919
JO - Rheumatology International
JF - Rheumatology International
IS - 8
ER -