Reducing the risk of anaphylaxis during anaesthesia: Guidelines for clinical practice

Paul Michel Mertes, M. C. Laxenaire, A. Lienhart, W. Aberer, J. Ring, W. J. Pichler, Pascal Demoly, G. Decroix, P. Dewachter, J. L. Guéant, L. Guilloux, D. Laroche, F. Leynadier, D. Longrois, J. M. Malinovsky, D. A. Moneret-Vautrin, C. Pecquet, M. Pinaud, P. Tréchot, D. VervloetF. Wessel, B. K. Ballmer-Weber, A. Barbaud, B. Bilo, J. Birnbaum, M. Bianca, B. Blömecke, K. Brockow, C. Christiansen, A. De Weck, C. Dzviga, M. Drouet, B. Eberlein-König, A. T. Frew, T. Fuchs, J. L. Guéant, R. M. Guéant-Rodriguez, C. Gutgesell, M. Hertl, G. Kanny, A. Kapp, M. Kidon, M. Kowalski, G. Marone, H. Merk, D. A. Moneret-Vautrin, C. Pascual-Marcos, B. Przybilla, E. Rebelo-Gomes, F. Rueff, A. Sabbah, J. Sainte Laudy, M. L. Sanz, E. Tas, A. Romano, M. J. Torres, D. Vervloet, B. Wedi, B. Wüthrich

Research output: Contribution to journalArticlepeer-review


These guidelines represent a consensus of experts in the field of immediate hypersensitivity reactions occurring during anaesthesia. They were based on international science, and implemented in France under the auspices of the French Society for Anaesthesia and Intensive Care (SFAR: Société Française d'Anesthésie et de Réanimation). Their aim was to provide the most valid, widely accepted, effective and easily teachable guidelines that current knowledge, research and experience can provide. This paper presents the main extracts of these recommendations with the most relevant clinical implications.


  • Anaesthesia
  • Anaphylaxis
  • Histamine
  • Hypersensitivity
  • Hypnotics
  • IgE
  • Latex
  • Neuromuscular blocking agents
  • Skin tests
  • Tryptase

ASJC Scopus subject areas

  • Immunology and Allergy


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