Recurrent respiratory infections in childhood: experience with a bacterial extract plus bacterial ribosomes (Immucytal®)

A. Fiocchi, R. Arancio, P. Cinquepalmi, M. Sala, G. V. Zuccotti, E. Riva, M. Giovannini

Research output: Contribution to journalArticlepeer-review

Abstract

A total of 60 children (mean age ±SD 7.6±3.5 years, range 2-14.2 years) with recurrent respiratory infections were treated with bacterial wall extract plus bacterial ribosomes (Immucytal) or placebo sprayed into the nostrils and oropharynx three times a day for 1 or 2-week periods over 3.5 months. The treatment was completed by 58 subjects; two patients in the placebo-treated group were withdrawn, one for poor compliance and the other because of headaches. Respiratory symptoms improved from the first month in the Immucytal treated children, but not in the placebo group, with a reduction in the incidence of infections in the upper and lower airways. No changes were noted in respiratory function parameters. Treatment with Immucytal significantly increased serum immunoglobulin A (P

Original languageEnglish
Pages (from-to)50-60
Number of pages11
JournalJournal of International Medical Research
Volume18
Issue number1
Publication statusPublished - 1990

Keywords

  • bacterial ribosomes
  • cell-mediated immunity
  • Membrane glycoprotein
  • paediatrics
  • respiratory infections

ASJC Scopus subject areas

  • Medicine(all)

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