Re-irradiation of metastatic spinal cord compression: A feasibility study by volumetric-modulated arc radiotherapy for in-field recurrence creating a dosimetric hole on the central canal

Pietro Mancosu; Piera Navarria; Mario Bignardi; Luca Cozzi; Antonella Fogliata; Paola Lattuada; Armando Santoro; Gaetano Urso; Sabrina Vigorito; Marta Scorsetti

doi:10.1016/j.radonc.2009.11.010

Re-irradiation of metastatic spinal cord compression: A feasibility study by volumetric-modulated arc radiotherapy for in-field recurrence creating a dosimetric hole on the central canal

Pietro Mancosu, Piera Navarria, Mario Bignardi, Luca Cozzi, Antonella Fogliata, Paola Lattuada, Armando Santoro, Gaetano Urso, Sabrina Vigorito, Marta Scorsetti

Research output: Contribution to journal › Article › peer-review

Abstract

When local recurrences arise within an irradiated region involving metastatic spinal cord compression, the dose limit to the spinal cord reduces the chance to re-treat the patient by 3D-conformational RT technique. The possibility of using volumetric modulated arc RT by RapidArc was evaluated for dose sparing at spinal cord level and preserving target coverage. A clinically satisfactory PTV coverage and dose sparing to the spinal cord were obtained. An upcoming trial on patients will provide clinical outcomes.

Original language	English
Pages (from-to)	67-70
Number of pages	4
Journal	Radiotherapy and Oncology
Volume	94
Issue number	1
DOIs	https://doi.org/10.1016/j.radonc.2009.11.010
Publication status	Published - Jan 2010

Keywords

Metastatic spinal cord compression-MSCC
Radiotherapy
RapidArc
Re-irradiation
Volumetric modulated arc therapy

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Hematology

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10.1016/j.radonc.2009.11.010

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Mancosu, P., Navarria, P., Bignardi, M., Cozzi, L., Fogliata, A., Lattuada, P., Santoro, A., Urso, G., Vigorito, S., & Scorsetti, M. (2010). Re-irradiation of metastatic spinal cord compression: A feasibility study by volumetric-modulated arc radiotherapy for in-field recurrence creating a dosimetric hole on the central canal. Radiotherapy and Oncology, 94(1), 67-70. https://doi.org/10.1016/j.radonc.2009.11.010

Re-irradiation of metastatic spinal cord compression : A feasibility study by volumetric-modulated arc radiotherapy for in-field recurrence creating a dosimetric hole on the central canal. / Mancosu, Pietro ; Navarria, Piera; Bignardi, Mario et al.

In: Radiotherapy and Oncology, Vol. 94, No. 1, 01.2010, p. 67-70.

Research output: Contribution to journal › Article › peer-review

Mancosu, P , Navarria, P, Bignardi, M, Cozzi, L, Fogliata, A, Lattuada, P, Santoro, A, Urso, G, Vigorito, S & Scorsetti, M 2010, 'Re-irradiation of metastatic spinal cord compression: A feasibility study by volumetric-modulated arc radiotherapy for in-field recurrence creating a dosimetric hole on the central canal', Radiotherapy and Oncology, vol. 94, no. 1, pp. 67-70. https://doi.org/10.1016/j.radonc.2009.11.010

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AU - Santoro, Armando

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Re-irradiation of metastatic spinal cord compression: A feasibility study by volumetric-modulated arc radiotherapy for in-field recurrence creating a dosimetric hole on the central canal

Abstract

Keywords

ASJC Scopus subject areas

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