STUDIO PROSPETTICO RANDOMIZZATO CON INTERFERONE (IFN) VS MITOMICINA-C (MMC) NEI TUMORI SUPERFICIALI DELLA VESCICA. RISULTATI PRELIMINARI SU 287 PAZIENTI

A. Curotto; M. Medica; R. Franchini; M. Schenone; M. Cussotto; F. Boccardo; D. Guarneri; A. Rubagotti; C. Pegoraro; E. Pozzi; G. Saracino; G. Martorana; L. Giuliani

STUDIO PROSPETTICO RANDOMIZZATO CON INTERFERONE (IFN) VS MITOMICINA-C (MMC) NEI TUMORI SUPERFICIALI DELLA VESCICA. RISULTATI PRELIMINARI SU 287 PAZIENTI

Translated title of the contribution: Randomized prospective study of interferon versus mitomycin-C in superficial tumors of the bladder. Preliminary results in 287 patients

A. Curotto, M. Medica, R. Franchini, M. Schenone, M. Cussotto, F. Boccardo, D. Guarneri, A. Rubagotti, C. Pegoraro, E. Pozzi, G. Saracino, G. Martorana, L. Giuliani

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

A multicentre, randomized study was carried out to compare the efficacy of prophylactic intravesical Mitomycin C vs Interferon, in terms of recurrences and progression, in superficial bladder tumours. After complete TURB, 287 patients with Ta-G2 and T1-G1/G2 were randomized to receive IFN 50 M IU or MMC 40 mg both diluted in 50 ml of 0.9% NaCl, once a week for 8 weeks. After a mean follow-up of 24 months (6-29), 34 local relapses (24.1%) occurred in the arm with MMC and 45 (30.8%) in the amr with IFN. No significant differences were found.

Translated title of the contribution	Randomized prospective study of interferon versus mitomycin-C in superficial tumors of the bladder. Preliminary results in 287 patients
Original language	Italian
Pages (from-to)	109-110
Number of pages	2
Journal	Acta Urologica Italica
Volume	6
Issue number	SUPPL. 4
Publication status	Published - 1992

ASJC Scopus subject areas

Urology

Cite this

Curotto, A., Medica, M., Franchini, R., Schenone, M., Cussotto, M., Boccardo, F., Guarneri, D., Rubagotti, A., Pegoraro, C., Pozzi, E., Saracino, G., Martorana, G., & Giuliani, L. (1992). STUDIO PROSPETTICO RANDOMIZZATO CON INTERFERONE (IFN) VS MITOMICINA-C (MMC) NEI TUMORI SUPERFICIALI DELLA VESCICA. RISULTATI PRELIMINARI SU 287 PAZIENTI. Acta Urologica Italica, 6(SUPPL. 4), 109-110.

Curotto, A, Medica, M, Franchini, R, Schenone, M, Cussotto, M, Boccardo, F, Guarneri, D, Rubagotti, A, Pegoraro, C, Pozzi, E, Saracino, G, Martorana, G & Giuliani, L 1992, 'STUDIO PROSPETTICO RANDOMIZZATO CON INTERFERONE (IFN) VS MITOMICINA-C (MMC) NEI TUMORI SUPERFICIALI DELLA VESCICA. RISULTATI PRELIMINARI SU 287 PAZIENTI', Acta Urologica Italica, vol. 6, no. SUPPL. 4, pp. 109-110.

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title = "STUDIO PROSPETTICO RANDOMIZZATO CON INTERFERONE (IFN) VS MITOMICINA-C (MMC) NEI TUMORI SUPERFICIALI DELLA VESCICA. RISULTATI PRELIMINARI SU 287 PAZIENTI",

abstract = "A multicentre, randomized study was carried out to compare the efficacy of prophylactic intravesical Mitomycin C vs Interferon, in terms of recurrences and progression, in superficial bladder tumours. After complete TURB, 287 patients with Ta-G2 and T1-G1/G2 were randomized to receive IFN 50 M IU or MMC 40 mg both diluted in 50 ml of 0.9% NaCl, once a week for 8 weeks. After a mean follow-up of 24 months (6-29), 34 local relapses (24.1%) occurred in the arm with MMC and 45 (30.8%) in the amr with IFN. No significant differences were found.",

author = "A. Curotto and M. Medica and R. Franchini and M. Schenone and M. Cussotto and F. Boccardo and D. Guarneri and A. Rubagotti and C. Pegoraro and E. Pozzi and G. Saracino and G. Martorana and L. Giuliani",

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language = "Italian",

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AU - Curotto, A.

AU - Medica, M.

AU - Franchini, R.

AU - Schenone, M.

AU - Cussotto, M.

AU - Boccardo, F.

AU - Guarneri, D.

AU - Rubagotti, A.

AU - Pegoraro, C.

AU - Pozzi, E.

AU - Saracino, G.

AU - Martorana, G.

AU - Giuliani, L.

PY - 1992

Y1 - 1992

N2 - A multicentre, randomized study was carried out to compare the efficacy of prophylactic intravesical Mitomycin C vs Interferon, in terms of recurrences and progression, in superficial bladder tumours. After complete TURB, 287 patients with Ta-G2 and T1-G1/G2 were randomized to receive IFN 50 M IU or MMC 40 mg both diluted in 50 ml of 0.9% NaCl, once a week for 8 weeks. After a mean follow-up of 24 months (6-29), 34 local relapses (24.1%) occurred in the arm with MMC and 45 (30.8%) in the amr with IFN. No significant differences were found.

AB - A multicentre, randomized study was carried out to compare the efficacy of prophylactic intravesical Mitomycin C vs Interferon, in terms of recurrences and progression, in superficial bladder tumours. After complete TURB, 287 patients with Ta-G2 and T1-G1/G2 were randomized to receive IFN 50 M IU or MMC 40 mg both diluted in 50 ml of 0.9% NaCl, once a week for 8 weeks. After a mean follow-up of 24 months (6-29), 34 local relapses (24.1%) occurred in the arm with MMC and 45 (30.8%) in the amr with IFN. No significant differences were found.

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M3 - Articolo

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JF - Acta Urologica Italica

IS - SUPPL. 4

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STUDIO PROSPETTICO RANDOMIZZATO CON INTERFERONE (IFN) VS MITOMICINA-C (MMC) NEI TUMORI SUPERFICIALI DELLA VESCICA. RISULTATI PRELIMINARI SU 287 PAZIENTI

Abstract

ASJC Scopus subject areas

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