Radiotherapy of brain metastases: Conventional versus concentrated treatment

M. G. Trovo, E. Minatel, A. Veronesi, A. de Paoli, G. Franchin, M. Roncadin, E. Galligioni, U. Tirelli, S. Tumolo, E. Grigoletto

Research output: Contribution to journalArticlepeer-review


From January 1975 to March 1981, 97 consecutive patients with brain metastases from various tumors were treated with cobalt-radiotherapy. Two successive treatment schedules were employed: the first 52 patients were treated according to a conventional schedule (30 or 40 Gy in 15 or 20 treatments over a 3 or 4 week period), while in the successive 45 patients a concentrated schedule was employed (2 series of 17 Gy in 2 sessions over a 3-day period, separated by an interval of 3 weeks). In the 87 evaluable patients, no significant difference was noted regarding the efficacy of radiotherapeutic treatment (25/47 and 20/40 partial remissions, respectively, with median survival of 4 and 3 months, respectively). Acute toxicity was more frequent with concentrated irradiation (approximately 20% of cases).

Original languageEnglish
Pages (from-to)20-22
Number of pages3
Issue number1
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cancer Research


Dive into the research topics of 'Radiotherapy of brain metastases: Conventional versus concentrated treatment'. Together they form a unique fingerprint.

Cite this