Radiochemical separations: Useful methods for the preparation of no-carrier-added solutions of different radionuclides for metabolic radiotherapy

C. Zona; F. Groppi; E. Persico; L. Canella; M. L. Bonardi; M. Chinol; K. Abbas; U. Holzwarth; N. Gibson

Radiochemical separations: Useful methods for the preparation of no-carrier-added solutions of different radionuclides for metabolic radiotherapy

C. Zona, F. Groppi, E. Persico, L. Canella, M. L. Bonardi, M. Chinol, K. Abbas, U. Holzwarth, N. Gibson

Istituto Europeo di Oncologia

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In Nuclear Medicine, radionuclides are used in the detection and the treatment for cancers and others diseases. We must obtain, for therapeutic purposes, solutions of radionuclides in the required chemical form, with an high specific activity (As). To reach our goal we must, first, obtain no-carrier-added (NCA) solutions. In this work we present different methods for the production of NCA radionuclides, based on either wct-chemistry, or the me and radio-chromatography. We set up four different methods: two for the preparation of the alpha emitter ²¹¹At, and two for the beta emitters ^186gRa and ⁹⁰Y. These radionuclides had been chosen because of their chemical and nuclear properties as their half-life, type, abundance and energy of emissions, that make them among the most promising radionuclides to label compounds for the mctabolic radionuclide therapy.

Original language	English
Title of host publication	Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications - Proceedings of the 10th Conference
Pages	711-715
Number of pages	5
Publication status	Published - 2008
Event	International Conference on Advanced Technology and Particle Physics, ICATPP 2007 - Como, Italy Duration: Oct 8 2007 → Oct 12 2007

Other

Other	International Conference on Advanced Technology and Particle Physics, ICATPP 2007
Country/Territory	Italy
City	Como
Period	10/8/07 → 10/12/07

ASJC Scopus subject areas

Astronomy and Astrophysics
Nuclear and High Energy Physics

Cite this

Zona, C., Groppi, F., Persico, E., Canella, L., Bonardi, M. L., Chinol, M., Abbas, K., Holzwarth, U., & Gibson, N. (2008). Radiochemical separations: Useful methods for the preparation of no-carrier-added solutions of different radionuclides for metabolic radiotherapy. In Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications - Proceedings of the 10th Conference (pp. 711-715)

Radiochemical separations : Useful methods for the preparation of no-carrier-added solutions of different radionuclides for metabolic radiotherapy. / Zona, C.; Groppi, F.; Persico, E. et al.

Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications - Proceedings of the 10th Conference. 2008. p. 711-715.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Zona, C, Groppi, F, Persico, E, Canella, L, Bonardi, ML, Chinol, M, Abbas, K, Holzwarth, U & Gibson, N 2008, Radiochemical separations: Useful methods for the preparation of no-carrier-added solutions of different radionuclides for metabolic radiotherapy. in Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications - Proceedings of the 10th Conference. pp. 711-715, International Conference on Advanced Technology and Particle Physics, ICATPP 2007, Como, Italy, 10/8/07.

@inproceedings{a4517d7996664783b48ec722d2e4ff8e,

title = "Radiochemical separations: Useful methods for the preparation of no-carrier-added solutions of different radionuclides for metabolic radiotherapy",

abstract = "In Nuclear Medicine, radionuclides are used in the detection and the treatment for cancers and others diseases. We must obtain, for therapeutic purposes, solutions of radionuclides in the required chemical form, with an high specific activity (As). To reach our goal we must, first, obtain no-carrier-added (NCA) solutions. In this work we present different methods for the production of NCA radionuclides, based on either wct-chemistry, or the me and radio-chromatography. We set up four different methods: two for the preparation of the alpha emitter 211At, and two for the beta emitters 186gRa and 90Y. These radionuclides had been chosen because of their chemical and nuclear properties as their half-life, type, abundance and energy of emissions, that make them among the most promising radionuclides to label compounds for the mctabolic radionuclide therapy.",

author = "C. Zona and F. Groppi and E. Persico and L. Canella and Bonardi, {M. L.} and M. Chinol and K. Abbas and U. Holzwarth and N. Gibson",

year = "2008",

language = "English",

isbn = "9812819088",

pages = "711--715",

booktitle = "Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications - Proceedings of the 10th Conference",

note = "International Conference on Advanced Technology and Particle Physics, ICATPP 2007 ; Conference date: 08-10-2007 Through 12-10-2007",

}

TY - GEN

T1 - Radiochemical separations

T2 - International Conference on Advanced Technology and Particle Physics, ICATPP 2007

AU - Zona, C.

AU - Groppi, F.

AU - Persico, E.

AU - Canella, L.

AU - Bonardi, M. L.

AU - Chinol, M.

AU - Abbas, K.

AU - Holzwarth, U.

AU - Gibson, N.

PY - 2008

Y1 - 2008

N2 - In Nuclear Medicine, radionuclides are used in the detection and the treatment for cancers and others diseases. We must obtain, for therapeutic purposes, solutions of radionuclides in the required chemical form, with an high specific activity (As). To reach our goal we must, first, obtain no-carrier-added (NCA) solutions. In this work we present different methods for the production of NCA radionuclides, based on either wct-chemistry, or the me and radio-chromatography. We set up four different methods: two for the preparation of the alpha emitter 211At, and two for the beta emitters 186gRa and 90Y. These radionuclides had been chosen because of their chemical and nuclear properties as their half-life, type, abundance and energy of emissions, that make them among the most promising radionuclides to label compounds for the mctabolic radionuclide therapy.

AB - In Nuclear Medicine, radionuclides are used in the detection and the treatment for cancers and others diseases. We must obtain, for therapeutic purposes, solutions of radionuclides in the required chemical form, with an high specific activity (As). To reach our goal we must, first, obtain no-carrier-added (NCA) solutions. In this work we present different methods for the production of NCA radionuclides, based on either wct-chemistry, or the me and radio-chromatography. We set up four different methods: two for the preparation of the alpha emitter 211At, and two for the beta emitters 186gRa and 90Y. These radionuclides had been chosen because of their chemical and nuclear properties as their half-life, type, abundance and energy of emissions, that make them among the most promising radionuclides to label compounds for the mctabolic radionuclide therapy.

UR - http://www.scopus.com/inward/record.url?scp=84885934137&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885934137&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:84885934137

SN - 9812819088

SN - 9789812819086

SP - 711

EP - 715

BT - Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications - Proceedings of the 10th Conference

Y2 - 8 October 2007 through 12 October 2007

ER -

Radiochemical separations: Useful methods for the preparation of no-carrier-added solutions of different radionuclides for metabolic radiotherapy

Abstract

Other

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this