Quantified electroencephalogram as measurable parameter in geriatrics

Human EEG undergoes a gradual change during the life-span. In a population over 60 years of age, roughly four basic types of EEG may be differentiated. The purpose of the investigations was to establish whether the EEG may be used as a model for the evaluation of drugs in geriatrics. Under controlled conditions two hydrogenated derivatives of ergot were administered to aged patients and the effect was evaluated by means of EEG (spectral analysis) and clinical assessment (SCAG). A statistically significant correlation between EEG and clinical effect was found.