Granuloma jalinizzante del polmone. Studio clinico-patologico di 2 casi, con alcune originali osservazioni ultrastrutturali e revisione della letteratura

G. Vezzani; Alberto Cavazza; G. Rossi; G. Pasquinelli; P. Avanzini; S. Asioli; S. Piana; M. Chilosi

Granuloma jalinizzante del polmone. Studio clinico-patologico di 2 casi, con alcune originali osservazioni ultrastrutturali e revisione della letteratura

Translated title of the contribution: Pulmonary hyalinizing granuloma. Clinicopathologic study of 2 cases, with some original ultrastructural observations and review of the literature

G. Vezzani, Alberto Cavazza, G. Rossi, G. Pasquinelli, P. Avanzini, S. Asioli, S. Piana, M. Chilosi

Arcispedale Santa Maria Nuova

Research output: Contribution to journal › Article › peer-review

Abstract

Aim: To report the clinical, histological, immunohistochemical and ultrastructural features of 2 new cases of pulmonary hyalinizing granuloma. Results: Both patients were males: one, 72-year-old with retroperitoneal fibrosis, was asymptomatic, while the other, 67-year-old, presented with non productive cough. In both cases, a chest x-ray showed a solitary pulmonary nodule. Microscopically, the nodules were well circumscribed and composed of lamellae of hyalinized collagen. At the periphery, a more cellular rim consisting of lymphocytes, plasma cells and myofibroblasts was present. Immunohistochemical and ultrastructural examinations revealed myofibroblastic elements actively synthesizing collagen fibrils.

Translated title of the contribution	Pulmonary hyalinizing granuloma. Clinicopathologic study of 2 cases, with some original ultrastructural observations and review of the literature
Original language	Italian
Pages (from-to)	23-28
Number of pages	6
Journal	Pathologica
Volume	96
Issue number	1
Publication status	Published - Feb 2004

ASJC Scopus subject areas

Pathology and Forensic Medicine

Cite this

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title = "Granuloma jalinizzante del polmone. Studio clinico-patologico di 2 casi, con alcune originali osservazioni ultrastrutturali e revisione della letteratura",

abstract = "Aim: To report the clinical, histological, immunohistochemical and ultrastructural features of 2 new cases of pulmonary hyalinizing granuloma. Results: Both patients were males: one, 72-year-old with retroperitoneal fibrosis, was asymptomatic, while the other, 67-year-old, presented with non productive cough. In both cases, a chest x-ray showed a solitary pulmonary nodule. Microscopically, the nodules were well circumscribed and composed of lamellae of hyalinized collagen. At the periphery, a more cellular rim consisting of lymphocytes, plasma cells and myofibroblasts was present. Immunohistochemical and ultrastructural examinations revealed myofibroblastic elements actively synthesizing collagen fibrils.",

keywords = "Electron microscopy, Hyalinizing granuloma, Immunohistochemistry, Lung, Myofibroblasts",

author = "G. Vezzani and Alberto Cavazza and G. Rossi and G. Pasquinelli and P. Avanzini and S. Asioli and S. Piana and M. Chilosi",

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AU - Vezzani, G.

AU - Cavazza, Alberto

AU - Rossi, G.

AU - Pasquinelli, G.

AU - Avanzini, P.

AU - Asioli, S.

AU - Piana, S.

AU - Chilosi, M.

PY - 2004/2

Y1 - 2004/2

N2 - Aim: To report the clinical, histological, immunohistochemical and ultrastructural features of 2 new cases of pulmonary hyalinizing granuloma. Results: Both patients were males: one, 72-year-old with retroperitoneal fibrosis, was asymptomatic, while the other, 67-year-old, presented with non productive cough. In both cases, a chest x-ray showed a solitary pulmonary nodule. Microscopically, the nodules were well circumscribed and composed of lamellae of hyalinized collagen. At the periphery, a more cellular rim consisting of lymphocytes, plasma cells and myofibroblasts was present. Immunohistochemical and ultrastructural examinations revealed myofibroblastic elements actively synthesizing collagen fibrils.

AB - Aim: To report the clinical, histological, immunohistochemical and ultrastructural features of 2 new cases of pulmonary hyalinizing granuloma. Results: Both patients were males: one, 72-year-old with retroperitoneal fibrosis, was asymptomatic, while the other, 67-year-old, presented with non productive cough. In both cases, a chest x-ray showed a solitary pulmonary nodule. Microscopically, the nodules were well circumscribed and composed of lamellae of hyalinized collagen. At the periphery, a more cellular rim consisting of lymphocytes, plasma cells and myofibroblasts was present. Immunohistochemical and ultrastructural examinations revealed myofibroblastic elements actively synthesizing collagen fibrils.

KW - Electron microscopy

KW - Hyalinizing granuloma

KW - Immunohistochemistry

KW - Lung

KW - Myofibroblasts

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Granuloma jalinizzante del polmone. Studio clinico-patologico di 2 casi, con alcune originali osservazioni ultrastrutturali e revisione della letteratura

Abstract

ASJC Scopus subject areas

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