TY - JOUR
T1 - Psychopharmacological treatment with risperidone and psychotherapic- rehabilitative approaches in schizophrenia and personality disorders
AU - Laini, V.
AU - Arduini, A.
AU - Critelli, E.
AU - Rossetti, R.
AU - Mapelli, L.
AU - Boscati, L.
AU - Regispani, F.
AU - Orlandi, R.
AU - Papa, P.
AU - Mauri, M. C.
PY - 1999
Y1 - 1999
N2 - 20 out-patients, affected by Schizophrenia or Personality Disorders according to DSM-IV, treated with risperidone (RSP) at a mean dosage of 4.46 mg ± 1.35 SD for 12 months, were included in the study. 5 patients also benefitted from psychotherapy, 5 participated in rehabilitation and re- socialisation groups while 10 received psychoeducational/supportive interventions. BPRS and PANSS total score (mean values) showed a significant decrease during the study. No correlation between RSP dosage and RSP or its metabolite, 9 hydroxy-risperidone (9OH-RSP) plasma levels resulted. No linear relationship between RSP plasma levels or active moiety and clinical improvement was observed. RSP therapy facilitated the psychotherapeutic compliance, re-socialisation processes and participation in groups, improving patients quality of life and relational modalities.
AB - 20 out-patients, affected by Schizophrenia or Personality Disorders according to DSM-IV, treated with risperidone (RSP) at a mean dosage of 4.46 mg ± 1.35 SD for 12 months, were included in the study. 5 patients also benefitted from psychotherapy, 5 participated in rehabilitation and re- socialisation groups while 10 received psychoeducational/supportive interventions. BPRS and PANSS total score (mean values) showed a significant decrease during the study. No correlation between RSP dosage and RSP or its metabolite, 9 hydroxy-risperidone (9OH-RSP) plasma levels resulted. No linear relationship between RSP plasma levels or active moiety and clinical improvement was observed. RSP therapy facilitated the psychotherapeutic compliance, re-socialisation processes and participation in groups, improving patients quality of life and relational modalities.
KW - Psychotherapy-rehabilitative approach
KW - Risperidone
KW - Schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=0033400543&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033400543&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0033400543
SN - 0393-5310
VL - 15
SP - 209
EP - 213
JO - New Trends in Experimental and Clinical Psychiatry
JF - New Trends in Experimental and Clinical Psychiatry
IS - 4
ER -