Prostacyclin and human foetal circulation

G. Remuzzi, R. Misiani, D. Muratore, D. Marchesi, M. Livio, A. Schieppati, G. Mecca, G. de Gaetano, M. B. Donati

Research output: Contribution to journalArticlepeer-review

Abstract

Tissues from human umbilical cord arteries and placental veins generated much greater prostacyclin activity than vessels from normal adults. High prostacyclin generation could contribute to maintaining the low peripheral vascular resistance typical of foetal circulation in which blood pressure is low despite very high cardiac output.

Original languageEnglish
Pages (from-to)341-348
Number of pages8
JournalProstaglandins
Volume18
Issue number3
DOIs
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

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