Primary signet-ring cell carcinoma of the lung in an HIV-positive patient

Alberto Testori, Gianluca Perroni, Camilla De Carlo, Alessandro Crepaldi, Marco Alloisio, Ugo Cioffi

Research output: Contribution to journalArticlepeer-review


Primary lung signet-ring cell carcinomas are a rare entity and only a few cases of pure signet-ring cell carcinomas of the lung are reported in the English literature. They usually have an aggressive behavior and a poor prognosis because in most cases they are identified at an advanced stage. We present a unique case of primary signet-ring cell carcinoma of the lung because the patient was HIV positive, a heavy smoker, and also the tumor, discovered incidentally during chest x-ray, was a pure type of signet-ring cell carcinoma. Surgical therapy associated with chemoradiotherapy represents the gold standard in the care of these patients.

Original languageEnglish
Pages (from-to)1122-1125
Number of pages4
JournalThoracic Cancer
Issue number7
Publication statusPublished - Apr 2021


  • Carcinoma, Signet Ring Cell/pathology
  • Female
  • HIV Infections/complications
  • Humans
  • Lung/pathology
  • Middle Aged


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