Primary ovarian insufficiency: X chromosome defects and autoimmunity

Luca Persani; Raffaella Rossetti; Chiara Cacciatore; Marco Bonomi

doi:10.1016/j.jaut.2009.03.004

Primary ovarian insufficiency: X chromosome defects and autoimmunity

Luca Persani, Raffaella Rossetti, Chiara Cacciatore, Marco Bonomi

Fondazione Istituto Auxologico Italiano

Research output: Contribution to journal › Article › peer-review

Abstract

Premature ovarian failure (POF) is a primary ovarian defect characterized by absent menarche or premature depletion of ovarian follicles before the age of 40 years. However, in several instances the distinction between definitive or intermittent POF may be difficult on clinical bases, therefore the more appropriate term Primary Ovarian Insufficiency (POI) has been recently proposed and will be used in this review. POI is a heterogeneous disorder affecting approximately 1% of women

Original language	English
Pages (from-to)	35-41
Number of pages	7
Journal	Journal of Autoimmunity
Volume	33
Issue number	1
DOIs	https://doi.org/10.1016/j.jaut.2009.03.004
Publication status	Published - Aug 2009

Keywords

Amenorrhea
Autoimmune oophoritis
BMP15
DIAPH
FMR1
Folliculogenesis
Hypergonadotropic ovarian failure
Ovarian dysgenesis
Premature ovarian failure
Primary ovarian insufficiency
Turner syndrome
X chromosome

ASJC Scopus subject areas

Immunology
Immunology and Allergy

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10.1016/j.jaut.2009.03.004

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title = "Primary ovarian insufficiency: X chromosome defects and autoimmunity",

abstract = "Premature ovarian failure (POF) is a primary ovarian defect characterized by absent menarche or premature depletion of ovarian follicles before the age of 40 years. However, in several instances the distinction between definitive or intermittent POF may be difficult on clinical bases, therefore the more appropriate term Primary Ovarian Insufficiency (POI) has been recently proposed and will be used in this review. POI is a heterogeneous disorder affecting approximately 1% of women ",

keywords = "Amenorrhea, Autoimmune oophoritis, BMP15, DIAPH, FMR1, Folliculogenesis, Hypergonadotropic ovarian failure, Ovarian dysgenesis, Premature ovarian failure, Primary ovarian insufficiency, Turner syndrome, X chromosome",

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AU - Rossetti, Raffaella

AU - Cacciatore, Chiara

AU - Bonomi, Marco

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KW - Amenorrhea

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KW - Folliculogenesis

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KW - Primary ovarian insufficiency

KW - Turner syndrome

KW - X chromosome

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Primary ovarian insufficiency: X chromosome defects and autoimmunity

Abstract

Keywords

ASJC Scopus subject areas

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