Primary cutaneous B-cell lymphoma with a dermatomal distribution

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Primary cutaneous B-cell lymphomas (CBCLs) are indolent lymphoproliferative skin disorders with the only exception of the variant arising on the legs, which is characterized by a more aggressive clinical course. We report a case of CBCL unusual in that it presented with a dermatome-like distribution and showed early peripheral lymph node involvement. The other noteworthy finding is that rearrangement of the bcl-2 gene was detected by polymerase chain reaction in skin tissue samples. The bcl-2 rearrangement, which is usually absent in the classic CBCLs, is likely to play a role in the aggressive clinical behavior of the tumor, although further studies are necessary to confirm it. The hypothesis of a virus causing the dermatomal presentation is intriguing but there is no proof for such speculation at this point.

Original languageEnglish
Pages (from-to)884-886
Number of pages3
JournalJournal of the American Academy of Dermatology
Issue number5 II
Publication statusPublished - 1999

ASJC Scopus subject areas

  • Dermatology


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