TY - JOUR
T1 - Preventing adverse obstetric outcomes in women with genetic thrombophilia
AU - Grandone, Elvira
AU - Brancaccio, Vincenzo
AU - Colaizzo, Donatella
AU - Sciannamé, Natale
AU - Pavone, Giuseppe
AU - Di Minno, Giovanni
AU - Margaglione, Maurizio
PY - 2002
Y1 - 2002
N2 - Objective: To improve fetomaternal outcomes in women with obstetric complications and inherited causes of thrombophilia. Design: Clinical trial. Setting: Thrombophilic women with previous unexplained adverse outcomes. Patient(s): Twenty-five women with previous severe obstetric complications were treated during and after pregnancy. Intervention(s): Low fixed dose of heparin or aspirin. Main Outcome Measure(s): Fetomaternal outcome. Result(s): Low fixed dose of heparin were administered to 24 pregnant women, aspirin to 7. Overall, among 31 treated pregnant women, 28 (90.3%) compared to 4 of 58 (6.9%) in previous pregnancies had a good obstetric outcome. Two fetal losses
AB - Objective: To improve fetomaternal outcomes in women with obstetric complications and inherited causes of thrombophilia. Design: Clinical trial. Setting: Thrombophilic women with previous unexplained adverse outcomes. Patient(s): Twenty-five women with previous severe obstetric complications were treated during and after pregnancy. Intervention(s): Low fixed dose of heparin or aspirin. Main Outcome Measure(s): Fetomaternal outcome. Result(s): Low fixed dose of heparin were administered to 24 pregnant women, aspirin to 7. Overall, among 31 treated pregnant women, 28 (90.3%) compared to 4 of 58 (6.9%) in previous pregnancies had a good obstetric outcome. Two fetal losses
KW - Pregnancy complications
KW - Thrombophilia
KW - Thromboprophylaxis
UR - http://www.scopus.com/inward/record.url?scp=0036321722&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036321722&partnerID=8YFLogxK
U2 - 10.1016/S0015-0282(02)03222-3
DO - 10.1016/S0015-0282(02)03222-3
M3 - Article
C2 - 12137876
AN - SCOPUS:0036321722
SN - 0015-0282
VL - 78
SP - 371
EP - 375
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 2
ER -