Preoperative C-reactive protein level and outcome following coronary surgery

Mario Gaudino, Giuseppe Nasso, Felicita Andreotti, Giuseppe Minniti, Licia Iacoviello, Maria Benedetta Donati, Rocco Schiavello, Gianfederico Possati

Research output: Contribution to journalArticlepeer-review


Objective: It has been suggested that a preoperative level of C-reactive protein (CRP)>5mg/l is predictive of postoperative complications in cardiac surgery patients. Material and methods: Among 113 primary isolated coronary artery bypass patients, CRP was determined preoperatively and fibrinogen, interleukine 6, plasminogen activator inhibitor-1, prothrombin time, activated partial thromboplastin time, platelets and white blood cells count measured before surgery, 24, 48 and 72h thereafter and at hospital discharge. The clinical course of all cases was prospectively recorded. Data were then analysed according to the preoperative CRP level by dividing the patients into two groups (CRP>5mg/l or CRP5mg/l did not predict in-hospital postoperative complications nor influence the extent of the inflammatory activation in primary isolated coronary bypass patients.

Original languageEnglish
Pages (from-to)521-526
Number of pages6
JournalEuropean Journal of Cardio-thoracic Surgery
Issue number4
Publication statusPublished - Oct 2002


  • C-reactive protein
  • Coronary artery bypass

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery


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