Preliminary experience with the pH-triggered pacemaker

L. Cammilli, L. Alcidi, G. Papeschi, V. Wiechmann, L. Padeletti, G. Grassi

Research output: Contribution to journalArticlepeer-review


A cardiac pacemaker capable of responding to blood acidosis by change in its stimulation rate allows adjustment to a patient's metabolic needs. The blood pH is sensed by an iridium oxide electrode in the right atrium. During exercise, the venous pH decreases and the paced ventricular rate increases. If acidosis persists, the paced rate gradually returns to baseline and reaches it after about 70 minutes. A pH-triggered pacemaker has been implanted in a 72-year-old male. The pacemaker remained responsive one year after implant, increasing rate during exercise, cold pressor stress, ischemia of the arms and emotional stress.

Original languageEnglish
Pages (from-to)448-457
Number of pages10
JournalPACE - Pacing and Clinical Electrophysiology
Issue number4
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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