Postural analysis in time and frequency domains in patients with Ehlers-Danlos syndrome

Manuela Galli, Chiara Rigoldi, Claudia Celletti, Luca Mainardi, Nunzio Tenore, Giorgio Albertini, Filippo Camerota

Research output: Contribution to journalArticlepeer-review


The goal of this work is to analyze postural control in Ehlers-Danlos syndrome (EDS) participants in time and frequency domain.This study considered a pathological group composed by 22 EDS participants performing a postural test consisting in maintaining standing position over a force platform for 30. s in two conditions: open eyes (OE) and closed eyes (CE). In order to compare pathological group we acquired in the same conditions a control group composed by 20 healthy participants.The obtained center of pressure (COP) signal was analyzed in time and frequency domain using an AR model.Results revealed differences between pathological and control group: EDS participants pointed out difficulties in controlling COP displacements trying to keep it inside the BOS in AP direction and for this reason increased the use of ML mechanism in order to avoid the risk of fall. Also in CE conditions they demonstrated more difficulties in maintaining posture revealing the proprioceptive system is impaired, due to ligament laxity that characterized EDS participants.Frequency domain analysis showed no differences between the two groups, affirming that the changes in time domain reflected really the impairment to the postural control mechanism and not a different strategy assumed by EDS participants.These data could help in decision-making process to establish a correct rehabilitation approach, based on the reinforcing of muscle tone to supply the ligament laxity in order to prevent risks of falls and its consequences.

Original languageEnglish
Pages (from-to)322-325
Number of pages4
JournalResearch in Developmental Disabilities
Issue number1
Publication statusPublished - Jan 2011


  • Ehlers-Danlos syndrome
  • Hypermobility syndrome
  • Posture analysis

ASJC Scopus subject areas

  • Clinical Psychology
  • Developmental and Educational Psychology


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