TY - JOUR
T1 - Postoperative Gastroesophageal Reflux After Laparoscopic Heller-Dor for Achalasia
T2 - True Incidence with an Objective Evaluation
AU - Salvador, Renato
AU - Pesenti, Elisa
AU - Gobbi, Laura
AU - Capovilla, Giovanni
AU - Spadotto, Lorenzo
AU - Voltarel, Guerrino
AU - Cavallin, Francesco
AU - Nicoletti, Loredana
AU - Valmasoni, Michele
AU - Ruol, Alberto
AU - Merigliano, Stefano
AU - Costantini, Mario
PY - 2016/6/30
Y1 - 2016/6/30
N2 - Introduction: The most common complication after laparoscopic Heller-Dor (LHD) is gastroesophageal reflux disease (GERD). The present study aimed (a) to analyze the true incidence of postoperative reflux by objectively assessing a large group of LHD patients and (b) to see whether the presence of typical GERD symptoms correlates with the real incidence of postoperative reflux. Methods: After LHD, patients were assessed by means of a symptom score, endoscopy, esophageal manometry, and 24-h pH monitoring. Patients were assigned to three groups: those did not accept to perform 24-h pH monitoring (group NP); those with normal postoperative pH findings (group A); and those with pathological postoperative acid exposure (group B). Results: Four hundred sixty-three of the 806 LHD patients agreed to undergo follow-up 24-h pH monitoring. Normal pH findings were seen in 423 patients (group A, 91.4 %), while 40 (8.6 %) had a pathological acid exposure (group B). The median symptom scores were similar: 3.0 (IQR 0–8) in group A and 6.0 (IQR 0–10) in group B (p = 0.29). At endoscopy, the percentage of esophagitis was also similar (11 % in group A, 19 % in group B; p = 0.28). Conclusions: This study demonstrated that, after LHD was performed by experienced surgeons, the true incidence of postoperative GERD is very low. The incidence of this possible complication should be assessed by pH monitoring because endoscopic findings and symptoms may be misleading.
AB - Introduction: The most common complication after laparoscopic Heller-Dor (LHD) is gastroesophageal reflux disease (GERD). The present study aimed (a) to analyze the true incidence of postoperative reflux by objectively assessing a large group of LHD patients and (b) to see whether the presence of typical GERD symptoms correlates with the real incidence of postoperative reflux. Methods: After LHD, patients were assessed by means of a symptom score, endoscopy, esophageal manometry, and 24-h pH monitoring. Patients were assigned to three groups: those did not accept to perform 24-h pH monitoring (group NP); those with normal postoperative pH findings (group A); and those with pathological postoperative acid exposure (group B). Results: Four hundred sixty-three of the 806 LHD patients agreed to undergo follow-up 24-h pH monitoring. Normal pH findings were seen in 423 patients (group A, 91.4 %), while 40 (8.6 %) had a pathological acid exposure (group B). The median symptom scores were similar: 3.0 (IQR 0–8) in group A and 6.0 (IQR 0–10) in group B (p = 0.29). At endoscopy, the percentage of esophagitis was also similar (11 % in group A, 19 % in group B; p = 0.28). Conclusions: This study demonstrated that, after LHD was performed by experienced surgeons, the true incidence of postoperative GERD is very low. The incidence of this possible complication should be assessed by pH monitoring because endoscopic findings and symptoms may be misleading.
KW - Achalasia
KW - Gastroesophageal reflux
KW - GERD
KW - Heller myotomy
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U2 - 10.1007/s11605-016-3188-x
DO - 10.1007/s11605-016-3188-x
M3 - Article
AN - SCOPUS:84976485792
SN - 1091-255X
SP - 1
EP - 6
JO - Journal of Gastrointestinal Surgery
JF - Journal of Gastrointestinal Surgery
ER -