TY - JOUR
T1 - Posterior Circulation Endovascular Thrombectomy for Large Vessels Occlusion in Patients Presenting with NIHSS Score ≤ 10
AU - Alexandre, Andrea M.
AU - Valente, Iacopo
AU - Consoli, Arturo
AU - Trombatore, Pietro
AU - Scarcia, Luca
AU - Piano, Mariangela
AU - Limbucci, Nicola
AU - Gabrieli, Joseph Domenico
AU - Russo, Riccardo
AU - Caragliano, Antonio Armando
AU - Ruggiero, Maria
AU - Saletti, Andrea
AU - Lazzarotti, Guido Andrea
AU - Pileggi, Marco
AU - Cosottini, Mirco
AU - Pilato, Fabio
AU - Slomka, Artur
AU - Colò, Francesca
AU - Giubbolini, Francesca
AU - Frisullo, Giovanni
AU - Della Marca, Giacomo
AU - Broccolini, Aldobrando
AU - Pedicelli, Alessandro
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/12
Y1 - 2021/12
N2 - Mechanical thrombectomy (MT) is currently the gold standard treatment for ischemic stroke due to large vessel occlusion (LVO). However, the evidence of clinical usefulness of MT in posterior circulation LVO (pc-LVO) is still doubtful compared to the anterior circulation, especially in patients with mild neurological symptoms. The database of 10 high-volume stroke centers in Europe, including a period of three year and a half, was screened for patients with an acute basilar artery occlusion or a single dominant vertebral artery occlusion (“functional” BAO) presenting with a NIHSS ≤10, and with at least 3 months follow-up. A total of 63 patients were included. Multivariate analysis demonstrated that female gender (adjusted OR 0.04; 95% CI 0–0.84; p = 0.04) and combined technique (adj OR 0.001; 95% CI 0–0.81; p = 0.04) were predictors of worse outcome. Higher pc-ASPECTS (adj OR 4.75; 95% CI 1.33–16.94; p = 0.02) and higher Delta NIHSS (adj OR 2.06; 95% CI 1.16–3.65; p = 0.01) were predictors of better outcome. Delta NIHSS was the main predictor of good outcome at 90 days in patients with posterior circulation LVO presenting with NIHSS score ≤ 10.
AB - Mechanical thrombectomy (MT) is currently the gold standard treatment for ischemic stroke due to large vessel occlusion (LVO). However, the evidence of clinical usefulness of MT in posterior circulation LVO (pc-LVO) is still doubtful compared to the anterior circulation, especially in patients with mild neurological symptoms. The database of 10 high-volume stroke centers in Europe, including a period of three year and a half, was screened for patients with an acute basilar artery occlusion or a single dominant vertebral artery occlusion (“functional” BAO) presenting with a NIHSS ≤10, and with at least 3 months follow-up. A total of 63 patients were included. Multivariate analysis demonstrated that female gender (adjusted OR 0.04; 95% CI 0–0.84; p = 0.04) and combined technique (adj OR 0.001; 95% CI 0–0.81; p = 0.04) were predictors of worse outcome. Higher pc-ASPECTS (adj OR 4.75; 95% CI 1.33–16.94; p = 0.02) and higher Delta NIHSS (adj OR 2.06; 95% CI 1.16–3.65; p = 0.01) were predictors of better outcome. Delta NIHSS was the main predictor of good outcome at 90 days in patients with posterior circulation LVO presenting with NIHSS score ≤ 10.
KW - Basilar artery
KW - Endovascular thrombectomy
KW - Low NIHSS
KW - Posterior circulation stroke
KW - Stroke
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U2 - 10.3390/life11121423
DO - 10.3390/life11121423
M3 - Article
AN - SCOPUS:85122401436
SN - 0024-3019
VL - 11
JO - Life
JF - Life
IS - 12
M1 - 1423
ER -