Plasma levels of cyclophosphamide in patients under polychemotherapeutic regimens

L. Ottolenghi, L. Morasca, S. Marsoni, E. Piazza, E. Soresi, A. Libretti, S. Garattini

Research output: Contribution to journalArticlepeer-review


Plasma levels of non metabolized CPA were measured in two groups of lung cancer patients receiving polychemotherapy. There was extreme variability in the data obtained during the first hour after CPA administration. After this period of time a wide range of T 1/2 was found particularly in one of the two groups of patients. 'Border-line' patients (with T 1/2 at the upper or lower limbs of the range found) are discussed as regards the possible influence of ancillary treatment.

Original languageEnglish
Pages (from-to)123-127
Number of pages5
Issue number3
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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