Plasma levels of cyclophosphamide in patients under polychemotherapeutic regimens

L. Ottolenghi; L. Morasca; S. Marsoni; E. Piazza; E. Soresi; A. Libretti; S. Garattini

Plasma levels of cyclophosphamide in patients under polychemotherapeutic regimens

L. Ottolenghi, L. Morasca, S. Marsoni, E. Piazza, E. Soresi, A. Libretti, S. Garattini

Research output: Contribution to journal › Article › peer-review

Abstract

Plasma levels of non metabolized CPA were measured in two groups of lung cancer patients receiving polychemotherapy. There was extreme variability in the data obtained during the first hour after CPA administration. After this period of time a wide range of T 1/2 was found particularly in one of the two groups of patients. 'Border-line' patients (with T 1/2 at the upper or lower limbs of the range found) are discussed as regards the possible influence of ancillary treatment.

Original language	English
Pages (from-to)	123-127
Number of pages	5
Journal	Biomedicine
Volume	32
Issue number	3
Publication status	Published - 1980

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

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title = "Plasma levels of cyclophosphamide in patients under polychemotherapeutic regimens",

abstract = "Plasma levels of non metabolized CPA were measured in two groups of lung cancer patients receiving polychemotherapy. There was extreme variability in the data obtained during the first hour after CPA administration. After this period of time a wide range of T 1/2 was found particularly in one of the two groups of patients. 'Border-line' patients (with T 1/2 at the upper or lower limbs of the range found) are discussed as regards the possible influence of ancillary treatment.",

author = "L. Ottolenghi and L. Morasca and S. Marsoni and E. Piazza and E. Soresi and A. Libretti and S. Garattini",

year = "1980",

language = "English",

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T1 - Plasma levels of cyclophosphamide in patients under polychemotherapeutic regimens

AU - Ottolenghi, L.

AU - Morasca, L.

AU - Marsoni, S.

AU - Piazza, E.

AU - Soresi, E.

AU - Libretti, A.

AU - Garattini, S.

PY - 1980

Y1 - 1980

N2 - Plasma levels of non metabolized CPA were measured in two groups of lung cancer patients receiving polychemotherapy. There was extreme variability in the data obtained during the first hour after CPA administration. After this period of time a wide range of T 1/2 was found particularly in one of the two groups of patients. 'Border-line' patients (with T 1/2 at the upper or lower limbs of the range found) are discussed as regards the possible influence of ancillary treatment.

AB - Plasma levels of non metabolized CPA were measured in two groups of lung cancer patients receiving polychemotherapy. There was extreme variability in the data obtained during the first hour after CPA administration. After this period of time a wide range of T 1/2 was found particularly in one of the two groups of patients. 'Border-line' patients (with T 1/2 at the upper or lower limbs of the range found) are discussed as regards the possible influence of ancillary treatment.

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IS - 3

ER -

Plasma levels of cyclophosphamide in patients under polychemotherapeutic regimens

Abstract

ASJC Scopus subject areas

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