TY - JOUR
T1 - Physical and biological characterizations of a novel multiphase anodic spark deposition coating to enhance implant osseointegration
AU - Giordano, Carmen
AU - Chiesa, Roberto
AU - Sandrini, Enrico
AU - Cigada, Alberto
AU - Giavaresi, Gianluca
AU - Fini, Milena
AU - Giardino, Roberto
PY - 2005/12
Y1 - 2005/12
N2 - The present study assessed in vitro the short-term cellular response to surface physico-chemical properties of a new, purposed bioactive surface treatment called BioSpark™ performed on simply machined and on sand-blasted titanium. Material characterisation was carried out using scanning electron microscopy, energy dispersion spectroscopy, laser profilometry, and thin film X-ray diffraction. The in vitro biological study showed a suitable cellular response with adhesion and spreading level comparable for all the tested specimens. The proliferation analysis demonstrated that all the surfaces successfully supported cellular colonisation; in particular, higher cellular proliferation activity was observed on the BioSpark™-treated materials, with values higher than machined titanium. The results suggest that the BioSpark™ treatment represents a smart way to enhance osteoblastic cellular colonisation and thus improve osteointegration processes of machined and sandblasted titanium for orthopaedic and dental implants.
AB - The present study assessed in vitro the short-term cellular response to surface physico-chemical properties of a new, purposed bioactive surface treatment called BioSpark™ performed on simply machined and on sand-blasted titanium. Material characterisation was carried out using scanning electron microscopy, energy dispersion spectroscopy, laser profilometry, and thin film X-ray diffraction. The in vitro biological study showed a suitable cellular response with adhesion and spreading level comparable for all the tested specimens. The proliferation analysis demonstrated that all the surfaces successfully supported cellular colonisation; in particular, higher cellular proliferation activity was observed on the BioSpark™-treated materials, with values higher than machined titanium. The results suggest that the BioSpark™ treatment represents a smart way to enhance osteoblastic cellular colonisation and thus improve osteointegration processes of machined and sandblasted titanium for orthopaedic and dental implants.
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U2 - 10.1007/s10856-005-4732-5
DO - 10.1007/s10856-005-4732-5
M3 - Article
C2 - 16362225
AN - SCOPUS:29144451919
SN - 0957-4530
VL - 16
SP - 1221
EP - 1229
JO - Journal of Materials Science: Materials in Medicine
JF - Journal of Materials Science: Materials in Medicine
IS - 12
ER -