Pharmacological treatment of hip fractured patients in Italy: A simulation based on Tuscany regional database for the TARGET project

Prisco Piscitelli, Alessia Metozzi, Maria Luisa Brandi, Ranuccio Nuti, Carla Rizzuti, Elisa Orlandini, Loredano Giorni, Daniela Merlotti

Research output: Contribution to journalArticlepeer-review


Background: Italy is the Country with the highest life expectancy in the world, and over 75,000 elderly people experience a hip fracture each year. Objective: following the Tuscany TARGET protocol, we aimed to estimate the costs of pharmacological treatment in the hypothesis of treating all elderly Italian people with hip fractures. Methods: we analyzed the Tuscany healthcare system databases at the beginning of the Tuscany TARGET project for the prevention of hip fractures in elderly patients, and the Italian national hospitalizations records and DRGs databases concerning hip fractures occurred between 2000 and 2005. Results: costs sustained for pharmacological treatments effective in reducing the risk of subsequent hip fractures all over Italy would account for 17.5 million Euros, representing only 0.18% of the overall national pharmaceuticals expenditures, while the national healthcare service is currently spending more than 30% of the overall pharmaceuticals expenditures in providing cardiovascular-active drugs. Conclusions: The burden of hip fractures in the Italian elderly population is substantial and must be acknowledged as an important health problem. Specific preventive strategies, such as the Tuscany TARGET project should be implemented in all Italian regions.

Original languageEnglish
Pages (from-to)140-143
Number of pages4
JournalClinical Cases in Mineral and Bone Metabolism
Issue number2
Publication statusPublished - May 2010


  • Compliance
  • Costs
  • Hip fractures
  • Incidence
  • Osteoporosis
  • Treatment

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine


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