The analgesic properties of clonidine are correlated to the inhibitor action both on spinal level and on the noradrenergic tegmental nuclei, and, in particular, on the locus coeruleus, attenuating the painful perception because of the raising of the threshold and limiting the emotive states connected with pain. In a patient with a chronic painful benign syndrome as a result of post-myelitic medullary atrophy and cluster headache it has obtained analgesic effects on back and leg pain and on headache: the aim of such a study has been to show by transcranial Doppler sonography the pharmacological effects of clonidine on headache.
|Translated title of the contribution||Pharmacological effects of intrathecal clonidine in cluster headache studied by transcranial Doppler sonography|
|Number of pages||4|
|Publication status||Published - 1996|
ASJC Scopus subject areas
- Clinical Neurology