Pharmacogenomics in dermatology: From susceptibility genes to personalized therapy

Carlo Pincelli; Marco Pignatti; Riccardo G. Borroni

doi:10.1111/j.1600-0625.2009.00852.x

Pharmacogenomics in dermatology: From susceptibility genes to personalized therapy

Carlo Pincelli, Marco Pignatti, Riccardo G. Borroni

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

A significant proportion of patients with skin disease do not respond to treatment and adverse drug reactions are a common problem. Genetic factors are important determinants for both drug efficacy and toxicity. The fields of pharmacogenetics and pharmacogenomics examine inter- individual variations in the DNA sequence that are related to drug efficacy and toxicity. Here, we present pharmacogenomic data relevant to dermatology and explore the role of dermatologists in identifying patients who may respond to treatment or experience adverse drug reactions.

Original language	English
Pages (from-to)	337-349
Number of pages	13
Journal	Experimental Dermatology
Volume	18
Issue number	4
DOIs	https://doi.org/10.1111/j.1600-0625.2009.00852.x
Publication status	Published - 2009

Keywords

Adverse drug reactions
Atopic dermatitis
Melanoma
Pharmacogenetics
Pharmacogenomics
Psoriasis

ASJC Scopus subject areas

Dermatology
Molecular Biology
Biochemistry

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10.1111/j.1600-0625.2009.00852.x

Cite this

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Pharmacogenomics in dermatology: From susceptibility genes to personalized therapy

Abstract

Keywords

ASJC Scopus subject areas

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