PFO closure with only fluoroscopic guidance: 7 years real-world single centre experience

Antonio Mangieri, Cosmo Godino, Matteo Montorfano, Francesco Arioli, Isabella Rosa, Silvia Ajello, Daniela Piraino, Alberto Monello, Anna Giulia Pavon, Giacomo Viani, Valeria Magni, Alberto Cappelletti, Alberto Margonato, Antonio Colombo

Research output: Contribution to journalArticlepeer-review


Aims To evaluate the safety and the efficacy of fluoroscopy-guided only (Fluo-G) and of echocardiography-guided (Echo-G; trans-esophageal echocardiography - TEE - or intracardiac echocardiography-ICE) percutaneous closure of patent foramen ovale (PFO). Methods and Results Single center retrospective registry enrolling 368 consecutive patients (mean age 50.5 years) who underwent PFO closure between June 2004 and December 2011. Most patients had prior cryptogenic stroke (n=126; 34.2%), TIA (n=218; 51.1%); some of these had recurrent neurological events [multiple strokes n=28 (7.8%); multiple TIAs n=72 (18.6%)]. All the patients underwent a preprocedure TEE. PFO closure was performed with Echo-G in 187 patients (50.8%) (TEE n=69, 36.8% and ICE n=124, 66.3%). In Fluo-G cases, PFO with atrial septal aneurysm (ASA) was significantly less present (P

Original languageEnglish
Pages (from-to)105-112
Number of pages8
JournalCatheterization and Cardiovascular Interventions
Issue number1
Publication statusPublished - Jul 1 2015


  • intracardiac ultrasound
  • patent foramen ovale
  • percutaneous closure
  • transesophageal echocardiography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging


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