PET/CT and breast cancer

Maria Picchio; Cristina Messa; Barbara Zangheri; Claudio Landoni; Luigi Gianolli; Ferruccio Fazio

doi:10.1007/978-3-540-36781-9_17

PET/CT and breast cancer

Maria Picchio, Cristina Messa, Barbara Zangheri, Claudio Landoni, Luigi Gianolli, Ferruccio Fazio

IRCCS Ospedale San Raffaele

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

During the last decade, the application of positron emission tomography (PET) has remarkably improved the management of cancer patients. The radiotracer most widely used in clinical practice is the glucose analogue 2-[ ¹⁸F]-fluoro-2-deoxy-D-glucose (FDG). FDG-PET is showing increasing usefulness in the distinction between malignant and benign lesions, in disease staging, re-staging and therapy planning. Due to the lack of precise anatomic landmarks, PET may present limitations in lesion localization. In contrast, PET/computed tomography (CT), by directly combining functional and morphological aspects, provides more reliable anatomical details. The main advantage of combined PET/CT imaging is, in fact, its ability to accurately correlate abnormal metabolic changes detected on PET imaging to anatomic structures defined at CT imaging (Townsend 2001). With this chapter, the impact in breast cancer diagnosis of PET/CT will be evaluated and compared with PET alone, visually correlated with morphologic imaging obtained in a separate session.

Original language	English
Title of host publication	Breast Cancer: Nuclear Medicine in Diagnosis and Therapeutic Options
Publisher	Springer Berlin Heidelberg
Pages	217-226
Number of pages	10
ISBN (Print)	9783540367802
DOIs	https://doi.org/10.1007/978-3-540-36781-9_17
Publication status	Published - 2008

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-3-540-36781-9_17

Cite this

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title = "PET/CT and breast cancer",

abstract = "During the last decade, the application of positron emission tomography (PET) has remarkably improved the management of cancer patients. The radiotracer most widely used in clinical practice is the glucose analogue 2-[ 18F]-fluoro-2-deoxy-D-glucose (FDG). FDG-PET is showing increasing usefulness in the distinction between malignant and benign lesions, in disease staging, re-staging and therapy planning. Due to the lack of precise anatomic landmarks, PET may present limitations in lesion localization. In contrast, PET/computed tomography (CT), by directly combining functional and morphological aspects, provides more reliable anatomical details. The main advantage of combined PET/CT imaging is, in fact, its ability to accurately correlate abnormal metabolic changes detected on PET imaging to anatomic structures defined at CT imaging (Townsend 2001). With this chapter, the impact in breast cancer diagnosis of PET/CT will be evaluated and compared with PET alone, visually correlated with morphologic imaging obtained in a separate session.",

author = "Maria Picchio and Cristina Messa and Barbara Zangheri and Claudio Landoni and Luigi Gianolli and Ferruccio Fazio",

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T1 - PET/CT and breast cancer

AU - Picchio, Maria

AU - Messa, Cristina

AU - Zangheri, Barbara

AU - Landoni, Claudio

AU - Gianolli, Luigi

AU - Fazio, Ferruccio

PY - 2008

Y1 - 2008

N2 - During the last decade, the application of positron emission tomography (PET) has remarkably improved the management of cancer patients. The radiotracer most widely used in clinical practice is the glucose analogue 2-[ 18F]-fluoro-2-deoxy-D-glucose (FDG). FDG-PET is showing increasing usefulness in the distinction between malignant and benign lesions, in disease staging, re-staging and therapy planning. Due to the lack of precise anatomic landmarks, PET may present limitations in lesion localization. In contrast, PET/computed tomography (CT), by directly combining functional and morphological aspects, provides more reliable anatomical details. The main advantage of combined PET/CT imaging is, in fact, its ability to accurately correlate abnormal metabolic changes detected on PET imaging to anatomic structures defined at CT imaging (Townsend 2001). With this chapter, the impact in breast cancer diagnosis of PET/CT will be evaluated and compared with PET alone, visually correlated with morphologic imaging obtained in a separate session.

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BT - Breast Cancer: Nuclear Medicine in Diagnosis and Therapeutic Options

PB - Springer Berlin Heidelberg

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PET/CT and breast cancer

Abstract

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