Abstract
A total of 70 adult patients with epilepsy were included as being treated for no less than six months with one of the above: CBZ and PB, 20; PHT, 18; SV, 12. Each patient was investigated through history taking, physical examination and neurophysiological evaluation of the median, ulnar, sural and peroneal nerves using standardized methods. A diagnosis of polyneuropathy (PN) was made when electrophysiologic signs of peripheral nerve involvement were present in two or more nerves. Thirthy-two patients (45%) fulfilled the diagnostic criteria for PN and presented signs of sensory-motor lesion, with predominant involmement of the lower limbs and concurrent demyelinating and axonal damage, although all the drugs were implicated, abnormalities were found to a lesser extent among SV users.
| Translated title of the contribution | Peripheral neuropathy and antiepileptic drugs: A clinical and electrophysiological study of 70 patients on monotherapy |
|---|---|
| Original language | Italian |
| Pages (from-to) | 349-350 |
| Number of pages | 2 |
| Journal | Bollettino - Lega Italiana contro l'Epilessia |
| Issue number | 70-71 |
| Publication status | Published - 1990 |
ASJC Scopus subject areas
- Clinical Neurology