Percutaneous transluminal renal angioplasty in neurofibromatosis

E. Fossali, M. Minoja, R. Intermite, C. Spreafico, E. Casalini, F. Sereni

Research output: Contribution to journalArticlepeer-review


A 9-year-old boy with hypertension was found to have neurofibromatosis associated with stenosis of the right renal artery. Percutaneous transluminal angioplasty (PTA) was performed. Immediately post angioplasty angiography showed that the stenosis persisted, but over the next few days his blood pressure rapidly decreased and remained well controlled even when treatment was discontinued. The captopril stimulation test, performed after PTA, confirmed the return of plasma renin activity to normal values. A digital subtraction aortogram, performed 2.5 years after PTA, was unchanged. His blood pressure remained persistently normal, without anti-hypertensive agents. Based on these results, PTA is suggested as the first step in correcting renal artery stenosis due to neurofibromatosis. A complete anatomical resolution of the stenosis is probably not required since slight improvements in the renal artery lumen may be accompanied by important functional improvement.

Original languageEnglish
Pages (from-to)623-625
Number of pages3
JournalPediatric Nephrology
Issue number5
Publication statusPublished - Oct 1995


  • Neurofibromatosis
  • Percutaneous transluminal angioplasty
  • Renal artery stenosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology


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