Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 389-400 |
| Number of pages | 12 |
| Journal | Internal and Emergency Medicine |
| Volume | 16 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2021 |
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Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry. / Argano, Christiano; Scichilone, Nicola; Natoli, Giuseppe et al.
In: Internal and Emergency Medicine, Vol. 16, No. 2, 2021, p. 389-400.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry
AU - Argano, Christiano
AU - Scichilone, Nicola
AU - Natoli, Giuseppe
AU - Nobili, Alessandro
AU - Corazza, Gino Roberto
AU - Mannucci, Pier Mannuccio
AU - Perticone, Francesco
AU - Corrao, Salvatore
AU - Pietrangelo, Antonello
AU - Licata, Giuseppe
AU - Violi, Francesco
AU - Marengoni, Alessandra
AU - Salerno, Francesco
AU - Cesari, Matteo
AU - Tettamanti, Mauro
AU - Pasina, Luca
AU - Franchi, Carlotta
AU - Miglio, Gabriella
AU - Cortesi, Laura
AU - Ardoino, Ilaria
AU - Novella, Alessio
AU - Prisco, Domenico
AU - Silvestri, Elena
AU - Emmi, Giacomo
AU - Bettiol, Alessandra
AU - Caterina, Cenci
AU - Biolo, Gianni
AU - Zanetti, Michela
AU - Guadagni, Martina
AU - Zaccari, Michele
AU - Chiuch, Massimiliano
AU - Vanoli, Massimo
AU - Grignani, Giulia
AU - Pulixi, Edoardo Alessandro
AU - Bernardi, Mauro
AU - Bassi, Silvia Li
AU - Santi, Luca
AU - Zaccherini, Giacomo
AU - Lupattelli, Graziana
AU - Mannarino, Elmo
AU - Bianconi, Vanessa
AU - Paciullo, Francesco
AU - Alcidi, Riccardo
AU - Nuti, Ranuccio
AU - Valenti, Roberto
AU - Ruvio, Martina
AU - Cappelli, Silvia
AU - Palazzuoli, Alberto
AU - Girelli, Domenico
AU - Busti, Fabiana
AU - Marchi, Giacomo
AU - Barbagallo, Mario
AU - Dominguez, Ligia
AU - Cocita, Floriana
AU - Beneduce, Vincenza
AU - Plances, Lidia
AU - Mularo, Salvatore
AU - Raspanti, Massimo
AU - Cavallaro, Federica
AU - Zoli, Marco
AU - Lazzari, Ilaria
AU - Brunori, Mattia
AU - Fabbri, Elisa
AU - Magalotti, Donatella
AU - Arnò, Raffaella
AU - Pasini, Franco Laghi
AU - Capecchi, Pier Leopoldo
AU - Palasciano, Giuseppe
AU - Modeo, Maria Ester
AU - Di Gennaro, Carla
AU - Cappellini, Maria Domenica
AU - Maira, Diletta
AU - Di Stefano, Valeria
AU - Fabio, Giovanna
AU - Seghezzi, Sonia
AU - Mancarella, Marta
AU - De Amicis, Margherita Migone
AU - De Luca, Giacomo
AU - Scaramellini, Natalia
AU - Rossi, Paolo Dionigi
AU - Damanti, Sarah
AU - Clerici, Marta
AU - Conti, Federica
AU - Bonini, Giulia
AU - Ottolini, Barbara Brignolo
AU - Di Sabatino, Antonio
AU - Miceli, Emanuela
AU - Lenti, Marco Vincenzo
AU - Pisati, Martina
AU - Dominioni, Costanza Caccia
AU - Murialdo, Giovanni
AU - Marra, Alessio
AU - Cattaneo, Federico
AU - Pontremoli, Roberto
AU - Beccati, Valentina
AU - Nobili, Giulia
AU - Secchi, Maria Beatrice
AU - Ghelfi, Davide
AU - Anastasio, Luigi
AU - Sofia, Lucia
AU - Carbone, Maria
AU - Cipollone, Francesco
AU - Guagnano, Maria Teresa
AU - Valeriani, Emanuele
AU - Rossi, Ilaria
AU - Mancuso, Gerardo
AU - Calipari, Daniela
AU - Bartone, Mosè
AU - Delitala, Giuseppe
AU - Berria, Maria
AU - Pes, Chiara
AU - Delitala, Alessandro
AU - Muscaritoli, Maurizio
AU - Molfino, Alessio
AU - Petrillo, Enrico
AU - Zuccalà, Giuseppe
AU - D’Aurizio, Gabriella
AU - Romanelli, Giuseppe
AU - Zucchelli, Alberto
AU - Manzoni, Francesca
AU - Volpini, Andrea
AU - Picardi, Antonio
AU - Gentilucci, Umberto Vespasiani
AU - Gallo, Paolo
AU - Dell’Unto, Chiara
AU - Annoni, Giorgio
AU - Corsi, Maurizio
AU - Bellelli, Giuseppe
AU - Zazzetta, Sara
AU - Mazzola, Paolo
AU - Szabo, Hajnalka
AU - Bonfanti, Alessandra
AU - Arturi, Franco
AU - Succurro, Elena
AU - Rubino, Mariangela
AU - Tassone, Bruno
AU - Sesti, Giorgio
AU - Serra, Maria Grazia
AU - Bleve, Maria Antonietta
AU - Gasbarrone, Laura
AU - Sajeva, Maria Rosaria
AU - Brucato, Antonio
AU - Ghidoni, Silvia
AU - Fabris, Fabrizio
AU - Bertozzi, Irene
AU - Bogoni, Giulia
AU - Rabuini, Maria Victoria
AU - Cosi, Elisabetta
AU - Scarinzi, Paolo
AU - Amabile, Annalisa
AU - Omenetto, Elisabetta
AU - Prandini, Tancredi
AU - Manfredini, Roberto
AU - Fabbian, Fabio
AU - Boari, Benedetta
AU - De Giorgi, Alfredo
AU - Tiseo, Ruana
AU - De Giorgio, Roberto
AU - Paolisso, Giuseppe
AU - Rizzo, Maria Rosaria
AU - Borghi, Claudio
AU - Strocchi, Enrico
AU - Ianniello, Eugenia
AU - Soldati, Mario
AU - Sabbà, Carlo
AU - Vella, Francesco Saverio
AU - Suppressa, Patrizia
AU - Schilardi, Andrea
AU - Loparco, Francesca
AU - De Vincenzo, Giovanni Michele
AU - Comitangelo, Alessio
AU - Amoruso, Emanuele
AU - Fenoglio, Luigi
AU - Falcetta, Andrea
AU - Bracco, Christian
AU - Fracanzani Silvia Fargion, Anna L.
AU - Tiraboschi, Silvia
AU - Cespiati, Annalisa
AU - Oberti, Giovanna
AU - Sigon, Giordano
AU - Peyvandi, Flora
AU - Rossio, Raffaella
AU - Ferrari, Barbara
AU - Colombo, Giulia
AU - Agosti, Pasquale
AU - Monzani, Valter
AU - Savojardo, Valeria
AU - Folli, Christian
AU - Ceriani, Giuliana
AU - Pallini, Giada
AU - Dallegri, Franco
AU - Ottonello, Luciano
AU - Liberale, Luca
AU - Caserza, Lara
AU - Salam, Kassem
AU - Liberato, Nicola Lucio
AU - Tognin, Tiziana
AU - Bianchi, Giovanni Battista
AU - Giaquinto, Sabrina
AU - Purrello, Francesco
AU - Di Pino, Antonino
AU - Piro, Salvatore
AU - Rozzini, Renzo
AU - Falanga, Lina
AU - Spazzini, Elena
AU - Ferrandina, Camillo
AU - Montrucchio, Giuseppe
AU - Petitti, Paolo
AU - Peasso, Paolo
AU - Favale, Edoardo
AU - Poletto, Cesare
AU - Salmi, Raffaella
AU - Gaudenzi, Piergiorgio
AU - Perri, Ludovica
AU - Landolfi, Raffaele
AU - Montalto, Massimo
AU - Mirijello, Antonio
AU - Guasti, Luigina
AU - Castiglioni, Luana
AU - Maresca, Andrea
AU - Squizzato, Alessandro
AU - Campiotti, Leonardo
AU - Grossi, Alessandra
AU - Bertolotti, Marco
AU - Mussi, Chiara
AU - Lancellotti, Giulia
AU - Libbra, Maria Vittoria
AU - Dondi, Giulia
AU - Pellegrini, Elisa
AU - Carulli, Lucia
AU - Galassi, Matteo
AU - Grassi, Yasmine
AU - Perticone, Maria
AU - Battaglia, Rosa
AU - FIlice, Marco
AU - Maio, Raffaele
AU - Stanghellini, Vincenzo
AU - Ruggeri, Eugenio
AU - del Vecchio, Sara
AU - Salvi, Andrea
AU - Leonardi, Roberto
AU - Damiani, Giampaolo
AU - Capeci, William
AU - Gabrielli, Armando
AU - Mattioli, Massimo
AU - Martino, Giuseppe Pio
AU - Biondi, Lorenzo
AU - Pettinari, Pietro
AU - Ghio, Riccardo
AU - Col, Anna Dal
AU - Minisola, Salvatore
AU - Colangelo, Luciano
AU - Cilli, Mirella
AU - Labbadia, Giancarlo
AU - Afeltra, Antonella
AU - Marigliano, Benedetta
AU - Pipita, Maria Elena
AU - Castellino, Pietro
AU - Zanoli, Luca
AU - Pignataro, Samuele
AU - Gennaro, Alfio
AU - Blanco, Julien
AU - Saracco, Valter
AU - Fogliati, Marisa
AU - Bussolino, Carlo
AU - Mete, Francesca
AU - Gino, Miriam
AU - Cittadini, Antonio
AU - Vigorito, Carlo
AU - Arcopinto, Michele
AU - Salzano, Andrea
AU - Bobbio, Emanuele
AU - Marra, Alberto Maria
AU - Sirico, Domenico
AU - Moreo, Guido
AU - Gasparini, Francesca
AU - Prolo, Silvia
AU - Pina, Gloria
AU - Ballestrero, Alberto
AU - Ferrando, Fabio
AU - Berra, Sergio
AU - Dassi, Simonetta
AU - Nava, Maria Cristina
AU - Graziella, Bruno
AU - Baldassarre, Stefano
AU - Fragapani, Salvatore
AU - Gruden, Gabriella
AU - Investigators, on behalf of the REPOSI
PY - 2021
Y1 - 2021
N2 - Currently, chronic obstructive pulmonary disease (COPD) represents the fourth cause of death worldwide with significant economic burden. Comorbidities increase in number and severity with age and are identified as important determinants that influence the prognosis. In this observational study, we retrospectively analyzed data collected from the RePoSI register. We aimed to investigate comorbidities and outcomes in a cohort of hospitalized elderly patients with the clinical diagnosis of COPD. Socio-demographic, clinical characteristics and laboratory findings were considered. The association between variables and in-hospital, 3-month and 1-year follow-up were analyzed. Among 4696 in-patients, 932 (19.8%) had a diagnosis of COPD. Patients with COPD had more hospitalization, a significant overt cognitive impairment, a clinically significant disability and more depression in comparison with non-COPD subjects. COPD patients took more drugs, both at admission, in-hospital stay, discharge and 3-month and 1-year follow-up. 14 comorbidities were more frequent in COPD patients. Cerebrovascular disease was an independent predictor of in-hospital mortality. At 3-month follow-up, male sex and hepatic cirrhosis were independently associated with mortality. ICS-LABA therapy was predictor of mortality at in-hospital, 3-month and 1-year follow-up. This analysis showed the severity of impact of COPD and its comorbidities in the real life of internal medicine and geriatric wards.
AB - Currently, chronic obstructive pulmonary disease (COPD) represents the fourth cause of death worldwide with significant economic burden. Comorbidities increase in number and severity with age and are identified as important determinants that influence the prognosis. In this observational study, we retrospectively analyzed data collected from the RePoSI register. We aimed to investigate comorbidities and outcomes in a cohort of hospitalized elderly patients with the clinical diagnosis of COPD. Socio-demographic, clinical characteristics and laboratory findings were considered. The association between variables and in-hospital, 3-month and 1-year follow-up were analyzed. Among 4696 in-patients, 932 (19.8%) had a diagnosis of COPD. Patients with COPD had more hospitalization, a significant overt cognitive impairment, a clinically significant disability and more depression in comparison with non-COPD subjects. COPD patients took more drugs, both at admission, in-hospital stay, discharge and 3-month and 1-year follow-up. 14 comorbidities were more frequent in COPD patients. Cerebrovascular disease was an independent predictor of in-hospital mortality. At 3-month follow-up, male sex and hepatic cirrhosis were independently associated with mortality. ICS-LABA therapy was predictor of mortality at in-hospital, 3-month and 1-year follow-up. This analysis showed the severity of impact of COPD and its comorbidities in the real life of internal medicine and geriatric wards.
U2 - 10.1007/s11739-020-02412-1
DO - 10.1007/s11739-020-02412-1
M3 - Article
SN - 1828-0447
VL - 16
SP - 389
EP - 400
JO - Internal and Emergency Medicine
JF - Internal and Emergency Medicine
IS - 2
ER -