Panel Reactive Antibody Monitoring in Pediatric Patients Undergoing Ventricle Assist Device as a Bridge to Heart Transplantation

Giorgia Grutter; Antonio Amodeo; Gianluca Brancaccio; Francesco Parisi

doi:10.1111/aor.12016

Panel Reactive Antibody Monitoring in Pediatric Patients Undergoing Ventricle Assist Device as a Bridge to Heart Transplantation

Giorgia Grutter, Antonio Amodeo, Gianluca Brancaccio, Francesco Parisi

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

We describe the incidence and patterns of anti-human leukocyte antigens antibody production in a pediatric population undergoing ventricular assist device (VAD) implantation. Serial panel reactive antibody was obtained prior to VAD implant, during VAD support, and after orthotopic heart transplantation (OHT). Seven children (median age 15 months) underwent VAD support as bridge to OHT. Posttransplant sensitization occurred in 42% of VAD patients and in 14% during VAD support.

Original language	English
Pages (from-to)	435-438
Number of pages	4
Journal	Artificial Organs
Volume	37
Issue number	5
DOIs	https://doi.org/10.1111/aor.12016
Publication status	Published - May 2013

Keywords

Panel reactive antibody
Pediatric heart transplantation
Sensitization
Ventricle assist device

ASJC Scopus subject areas

Biomaterials
Biomedical Engineering
Bioengineering
Medicine (miscellaneous)

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10.1111/aor.12016

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abstract = "We describe the incidence and patterns of anti-human leukocyte antigens antibody production in a pediatric population undergoing ventricular assist device (VAD) implantation. Serial panel reactive antibody was obtained prior to VAD implant, during VAD support, and after orthotopic heart transplantation (OHT). Seven children (median age 15 months) underwent VAD support as bridge to OHT. Posttransplant sensitization occurred in 42% of VAD patients and in 14% during VAD support.",

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AU - Parisi, Francesco

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AB - We describe the incidence and patterns of anti-human leukocyte antigens antibody production in a pediatric population undergoing ventricular assist device (VAD) implantation. Serial panel reactive antibody was obtained prior to VAD implant, during VAD support, and after orthotopic heart transplantation (OHT). Seven children (median age 15 months) underwent VAD support as bridge to OHT. Posttransplant sensitization occurred in 42% of VAD patients and in 14% during VAD support.

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KW - Sensitization

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Panel Reactive Antibody Monitoring in Pediatric Patients Undergoing Ventricle Assist Device as a Bridge to Heart Transplantation

Abstract

Keywords

ASJC Scopus subject areas

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