Pain-related cerebral potentials in patients with frontal or parietal lobe lesions

Irene Daum; Christoph Braun; Gerlinde Riesch; Wolfgang Miltner; Hermann Ackermann; Markus M. Schugens; Niels Birbaumer

doi:10.1016/0304-3940(95)11916-K

Pain-related cerebral potentials in patients with frontal or parietal lobe lesions

Irene Daum, Christoph Braun, Gerlinde Riesch, Wolfgang Miltner, Hermann Ackermann, Markus M. Schugens, Niels Birbaumer

Istituto di Neuroriabilitazione Motoria San Camillo

Research output: Contribution to journal › Article › peer-review

Abstract

The present study investigated the processing of painful electrical stimuli in patients with unilateral frontal or parietal lobe damage and matched control subjects. Patients with frontal lesions showed increased pain thresholds when the stimuli were administered contralateral to the lesion. While the peak-to-peak amplitudes of the N150/P250 components of the somatosensory potentials increased linearly with stimulus intensity in the control subjects, the responses in the frontal group did not change significantly between stimulation at pain and tolerance threshold. There was no evidence for altered pain processing in patients with parietal lobe lesions. The findings of the present study support the hypothesis of an involvement of the frontal cortex in pain perception in humans.

Original language	English
Pages (from-to)	137-140
Number of pages	4
Journal	Neuroscience Letters
Volume	197
Issue number	2
DOIs	https://doi.org/10.1016/0304-3940(95)11916-K
Publication status	Published - Sept 8 1995

Keywords

Frontal lobe lesions
Pain processing
Somatosensory potentials

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/0304-3940(95)11916-K

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title = "Pain-related cerebral potentials in patients with frontal or parietal lobe lesions",

abstract = "The present study investigated the processing of painful electrical stimuli in patients with unilateral frontal or parietal lobe damage and matched control subjects. Patients with frontal lesions showed increased pain thresholds when the stimuli were administered contralateral to the lesion. While the peak-to-peak amplitudes of the N150/P250 components of the somatosensory potentials increased linearly with stimulus intensity in the control subjects, the responses in the frontal group did not change significantly between stimulation at pain and tolerance threshold. There was no evidence for altered pain processing in patients with parietal lobe lesions. The findings of the present study support the hypothesis of an involvement of the frontal cortex in pain perception in humans.",

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AU - Daum, Irene

AU - Braun, Christoph

AU - Riesch, Gerlinde

AU - Miltner, Wolfgang

AU - Ackermann, Hermann

AU - Schugens, Markus M.

AU - Birbaumer, Niels

PY - 1995/9/8

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AB - The present study investigated the processing of painful electrical stimuli in patients with unilateral frontal or parietal lobe damage and matched control subjects. Patients with frontal lesions showed increased pain thresholds when the stimuli were administered contralateral to the lesion. While the peak-to-peak amplitudes of the N150/P250 components of the somatosensory potentials increased linearly with stimulus intensity in the control subjects, the responses in the frontal group did not change significantly between stimulation at pain and tolerance threshold. There was no evidence for altered pain processing in patients with parietal lobe lesions. The findings of the present study support the hypothesis of an involvement of the frontal cortex in pain perception in humans.

KW - Frontal lobe lesions

KW - Pain processing

KW - Somatosensory potentials

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Pain-related cerebral potentials in patients with frontal or parietal lobe lesions

Abstract

Keywords

ASJC Scopus subject areas

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