TY - JOUR
T1 - Overweight Patients Operated on for Cancer of the Esophagus Survive Longer than Normal-Weight Patients
AU - Scarpa, Marco
AU - Cagol, Matteo
AU - Bettini, Silvia
AU - Alfieri, Rita
AU - Carraro, Amedeo
AU - Cavallin, Francesco
AU - Trevellin, Elisabetta
AU - Saadeh, Luca M.
AU - Ruol, Alberto
AU - Vettor, Roberto
AU - Ancona, Ermanno
AU - Castoro, Carlo
PY - 2013
Y1 - 2013
N2 - Background: Esophageal adenocarcinoma is often associated with obesity, and a 5 Kg m-2 increase in body mass index (BMI) has, in fact, been found to be strongly associated with the risk of this type of cancer (RR, 1.52; p <0.0001). Esophagectomy with lymphoadenectomy is the mainstay of therapy for these patients. The aim of this study was to assess and compare the surgical and oncological outcomes as well as the survival rates of underweight, normal weight, overweight, and obese patients following esophagectomy for esophageal cancer. Patients and Methods: Data relative to 1,127 patients with esophageal adenocarcinoma presenting at a specialized tertiary hospital (the Center of Esophageal Diseases for the Veneto Region) between 2000 and 2008 were prospectively collected. The 278 subjects whose BMI values before disease onset were available and underwent esophagectomy were enrolled in the study. Sixty-one of the 278 patients were classified as obese (BMI >30), 121 were classified as overweight (BMI, 25-29.9), 81 were classified as normal weight (BMI
AB - Background: Esophageal adenocarcinoma is often associated with obesity, and a 5 Kg m-2 increase in body mass index (BMI) has, in fact, been found to be strongly associated with the risk of this type of cancer (RR, 1.52; p <0.0001). Esophagectomy with lymphoadenectomy is the mainstay of therapy for these patients. The aim of this study was to assess and compare the surgical and oncological outcomes as well as the survival rates of underweight, normal weight, overweight, and obese patients following esophagectomy for esophageal cancer. Patients and Methods: Data relative to 1,127 patients with esophageal adenocarcinoma presenting at a specialized tertiary hospital (the Center of Esophageal Diseases for the Veneto Region) between 2000 and 2008 were prospectively collected. The 278 subjects whose BMI values before disease onset were available and underwent esophagectomy were enrolled in the study. Sixty-one of the 278 patients were classified as obese (BMI >30), 121 were classified as overweight (BMI, 25-29.9), 81 were classified as normal weight (BMI
KW - BMI
KW - Esophageal cancer
KW - Esophagectomy
KW - Obesity
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U2 - 10.1007/s11605-012-2023-2
DO - 10.1007/s11605-012-2023-2
M3 - Article
C2 - 22972011
AN - SCOPUS:84872612572
SN - 1091-255X
VL - 17
SP - 218
EP - 227
JO - Journal of Gastrointestinal Surgery
JF - Journal of Gastrointestinal Surgery
IS - 2
ER -